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Functionalized Magnetic Nanoparticles and Methods of Use Thereof

  • US 20080206146A1
  • Filed: 03/21/2006
  • Published: 08/28/2008
  • Est. Priority Date: 03/21/2005
  • Status: Abandoned Application
First Claim
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1. A pharmaceutical composition comprising:

  • a) a functionalized magnetic nanoparticle (MNP) comprising a functional group that has differential affinity for a tissue in the brain, wherein said functionalized magnetic nanoparticle is capable, when introduced into the bloodstream of a mammalian subject, of crossing the blood-brain barrier of said subject and binding specifically to the brain tissue; and

    b) a pharmaceutically acceptable carrier.

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