COATED MEDICAL IMPLANTS AND LENSES
First Claim
1. A coated medical implant configured to be secured in or adjacent to a body tissue, the coated medical implant comprising:
- an implant body having a body surface; and
a coating formed on at least a portion of the body surface, the coating comprising;
a first chemical component formed by plasma deposition directly on the body surface, the first chemical component comprising an amine functional group,a second chemical component chemically bonded to the first chemical component and having at least one free carboxylate functional group after bonding to the first chemical component, anda third chemical component chemically bonded to the at least one free carboxylate functional group.
2 Assignments
0 Petitions
Accused Products
Abstract
Coated medical implants have an implant body configured for securing in or adjacent to body tissue of a patient. The implant body has an implant surface and a coating is formed on at least a portion of the implant surface. The coating includes a coating outer surface of a first chemical component that is chemically bonded to a carboxylate functionality of a second chemical component. The second chemical component is immobilized by amide linkage to an underlying third chemical component that is plasma coated directly onto implant body surfaces. The coating either inhibits or prevents the adhesion of protein and/or cellular proliferation or may be a non-fouling coating.
31 Citations
20 Claims
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1. A coated medical implant configured to be secured in or adjacent to a body tissue, the coated medical implant comprising:
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an implant body having a body surface; and a coating formed on at least a portion of the body surface, the coating comprising; a first chemical component formed by plasma deposition directly on the body surface, the first chemical component comprising an amine functional group, a second chemical component chemically bonded to the first chemical component and having at least one free carboxylate functional group after bonding to the first chemical component, and a third chemical component chemically bonded to the at least one free carboxylate functional group. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A coated medical implant comprising:
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an implant body comprising an implant body surface; and a coating formed on the implant body surface, the coating inhibiting protein adhesion and cellular adhesion to the implant body, the coating comprising a coating outer surface comprising a third chemical component, the third chemical component bonded by an amide linkage to a carboxylate functionality of an second chemical component, the second chemical component immobilized by an amide linkage to an underlying first chemical component comprising an amine that is plasma coated directly onto the implant body surface. - View Dependent Claims (12, 13, 14, 15, 16)
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17. A coated medical implant comprising:
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an optically transparent lens body comprising lens outer surfaces; and a coating formed on at least a portion of the lens outer surfaces, the coating comprising a coating outer surface comprising a third chemical component, the third chemical component bonded by an amide linkage to a carboxylate functionality of a second chemical component having an average molecular weight in a range from about 2,000 to about 10,000, the second chemical component immobilized by an amide linkage to an underlying first chemical component comprising an amine that is plasma coated directly onto the at least a portion of the lens outer surfaces. - View Dependent Claims (18, 19, 20)
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Specification