Integrated surface-machined micro flow controller method and apparatus

• US 20080210306A1
• Filed: 09/06/2006
• Published: 09/04/2008
• Est. Priority Date: 01/15/2003
• Status: Abandoned Application

• Current Assignee: California Institute of Technology
• Original Assignee: California Institute of Technology
• Inventors: Tai, Yu-Chong, Shih, Jason, Xie, Jun
• Application Number:
  US11/515,794
• Publication Number:
  US 20080210306A1
• Time in Patent Office: Days
• US Class Current: 137/13
• CPC Class Codes: F16K 2099/0074 using photolithography, e.g. etching
• CPC Class Codes: F16K 2099/008 Multi-layer fabrications
• CPC Class Codes: F16K 99/0001 Microvalves microdevices B81B1/00; manufacture or treatment of devices or systems in or on a substrate B81C1/00; microfluidic structures B01L3/5027; micropumps F04B19/006
• CPC Class Codes: F16K 99/0015 Diaphragm or membrane valves
• CPC Class Codes: F16K 99/0044 using thermo-electric means
• CPC Class Codes: F16K 99/0051 using electrostatic means
• CPC Class Codes: F16K 99/0061 actuated by an expanding gas or liquid volume
• CPC Class Codes: G01F 1/6845 Micromachined devices
• CPC Class Codes: G01F 15/005 Valves valves in general F16K
• CPC Class Codes: G05D 7/0694 by action on throttling means or flow sources of very small size, e.g. microfluidics microvalves F16K99/0001; microstructural devices per se B81B
• CPC Class Codes: Y10T 137/0391 Affecting flow by the addition of material or energy
• CPC Class Codes: Y10T 29/49412 with assembly, disassembly or composite article making

Abstract

A surface-micromachined mass flow controller (MFC) comprises an electrostatically actuated microvalve integrated with a thermal flow sensor. The microvalve comprises a normally-open diaphragm defining an aperture allowing fluid communication between first and second flow channels. The diaphragm includes a second electrode actuable toward a valve seat including a first electrode. Fabricated utilizing a multilayer Parylene process, the active microvalve and the flow sensor are integrated onto a single chip to perform closed-loop flow control. For flow control, both Pulse Width Modulation (PWM) and actuation voltage adjustment are demonstrated.

Claims

1. An electrostatic valve device comprising:

a substrate;

a first fluid channel disposed on the substrate;

a second fluid channel disposed on the substrate;

a polymer based diaphragm coupled between the first fluid channel and the second fluid channel;

an orifice disposed within a portion of the polymer diaphragm, the orifice being adapted to provide fluid communication between the first fluid channel and the second fluid channel;

a first electrode coupled to the substrate;

a second electrode coupled to the polymer based diaphragm and separated from the first electrode by the first fluid channel; and

a power source coupled between the first electrode and the second electrode, the power source being adapted to actuate the diaphragm to block fluid communication between the first fluid channel and the second fluid channel through the orifice.

2. The device of claim 1 wherein the first fluid channel and the second fluid channel contain liquid.

3. The device of claim 1 wherein the first fluid channel and the second fluid channel contain gas.

4. The device of claim 1 wherein at least one of the first and second fluid channels is characterized by a height of less than 5 micron.

5. The device of claim 1 wherein both the first and second fluid channels are characterized by a height of equal or larger than 5 micron.

6. The device of claim 1 wherein first fluid channel has a height that is different from a height of the second fluid channel.

7. The device of claim 1 wherein the polymer based diaphragm has a diameter ranging from 10 to 1000 micron.

8. The device of claim 1 wherein the polymer diaphragm is characterized by a diameter larger than 1000 micron.

9. The device of claim 1 wherein the polymer diaphragm is characterized by a thickness ranging from 0.1 to 10 micron.

10. The device of claim 1 wherein the polymer based diaphragm is characterized by a thickness of larger than 10 micron.

11. The device of claim 1 wherein the second electrode is embedded within the polymer based diaphragm.

12. The device of claim 1 wherein the substrate is made of a material selected from silicon or glass.

13. The device of claim 1 wherein the polymer based diaphragm comprises a material selected from parylene, polyimide, or silicone.

14. The device of claim 1 wherein at least one of the first and second electrodes comprises a conducting material selected from the group consisting of chrome, gold, aluminum, titanium, platinum, and doped polysilicon.

15. The device of claim 1 further comprising a flow sensor coupled to one of the first and the second flow channels, the flow sensor configured to provide flow measurement information to the valve to achieve feedback flow control.

16. A method for fabricating a micro fluidic device, the method comprising:

providing a substrate;

forming a first electrically conducting layer overlying the substrate;

patterning the first electrode layer to form a first electrode element;

forming a first polymer based layer overlying the first electrode element and the substrate;

forming a first sacrificial layer overlying the first polymer based layer;

forming a second polymer based layer overlying the first sacrificial layer, the second polymer layer defining an aperture;

forming a second electrically conducting layer overlying the first polymer based layer;

patterning the second electrode layer to form a second electrode element associated with the first electrode element, the second electrode layer excluded from the aperture;

forming a third polymer based layer overlying the second electrode element to sandwich the second electrode element between the second polymer based layer and the third polymer based layer, the third polymer based layer also excluded from the aperture;

forming a second sacrificial layer overlying the third polymer based layer and the first sacrificial layer within the aperture;

forming a fourth polymer based layer overlying the second sacrificial layer; and

releasing the first and second sacrificial layers to define respective first and second flow channels in fluid communication through the aperture.

17. The method of claim 16 wherein forming the first and second sacrificial layers comprises patterning photoresist.

18. The method of claim 17 wherein releasing the first and second sacrificial layers comprises exposing the first and second sacrificial layers to acetone.

19. The method of claim 18 further comprising exposing the first and second sacrificial layers to isopropyl alcohol once the first and second flow channels have been substantially defined.

20. The method of claim 16 wherein the first polymer based layer, the second polymer based layer, and third polymer based layer are provided using chemical vapor deposition of Parylene.

21. The method of claim 16 wherein:

patterning the second electrode layer also forms a heating element, the heating element in thermal communication with one of the first and the second flow channel; and

releasing the first sacrificial layer defines a cavity providing thermal isolation of the heating element.

22. A method of controlling a flow of fluid comprising:

providing a first polymer based layer overlying a first electrode supported by a substrate;

defining a flow channel between the first polymer layer and a diaphragm comprising a second electrode sandwiched between second and third polymer based layers, the second electrode and second and third polymer based layers defining an aperture; and

selectively applying a potential difference between the first and second electrodes to draw the second electrode toward the first electrode, thereby causing the diaphragm to seat on the first polymer layer and block a flow of fluid through the aperture.

23. The method of claim 22 further comprising:

defining a thermal isolation cavity between the first polymer layer and a heating element sandwiched between the second and third polymer layers and in thermal communication with the flow channel;

detecting a voltage change in the heating element reflecting a velocity of fluid flow through the flow channel; and

changing the potential difference based on the voltage change.

24. The method of claim 22 wherein defining the flow channel comprises:

patterning a first sacrificial layer over the first polymer layer;

forming a second sacrificial layer in the aperture over a first sacrificial layer; and

removing the first and second sacrificial layers.

25. The method of claim 24 wherein:

patterning a first and second sacrificial layers comprises patterning photoresist; and

removing the first and second sacrificial layers comprises introducing acetone.

26. The method of claim 22 wherein the first polymer based layer, the second polymer based layer, and the third polymer based layer are provided using chemical vapor deposition of Parylene.