METHOD OF DETERMINING ANALYTE CONCENTRATION IN A SAMPLE USING INFRARED TRANSMISSION DATA
First Claim
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1. A method of determining an optical pathlength of a sample comprising water and a blood protein, the method comprising:
- measuring an optical absorption of the sample at an isosbestic wavelength for water and a blood protein;
using the optical absorption to calculate-independent of water or blood protein concentration—
the optical pathlength of the sample; and
providing the optical pathlength to a user.
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Abstract
A method determines an analyte concentration in a sample. The sample includes the analyte and a substance. The method includes providing absorption data of the sample. The method further includes providing reference absorption data of the substance. The method further includes calculating a substance contribution of the absorption data. The method further includes subtracting the substance contribution from the absorption data, thereby providing corrected absorption data substantially free of a contribution from the substance.
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Citations
9 Claims
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1. A method of determining an optical pathlength of a sample comprising water and a blood protein, the method comprising:
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measuring an optical absorption of the sample at an isosbestic wavelength for water and a blood protein; using the optical absorption to calculate-independent of water or blood protein concentration—
the optical pathlength of the sample; andproviding the optical pathlength to a user. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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Specification