PHARMACEUTICAL PREPARATION CONTAINING A GESTAGEN, AND KIT AND METHOD FOR TREATING ENDOMETRIOSIS USING THE PREPARATION
First Claim
1. A pharmaceutical preparation for treating endometriosis, said pharmaceutical preparation comprising a daily dose of a gestagen with anti-androgenic activity, which is up to twice that for inhibiting ovulation, and one or more pharmaceutically acceptable aids and/or carriers.
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Accused Products
Abstract
The pharmaceutical preparation for treating endometriosis contains at least 28, preferably 30, daily dose units, each of which contain dienogest, cyproterone acetate, or chlormadinone acetate at a daily dose that is at most twice that required to inhibit ovulation together with one or more pharmaceutical aids and/or carriers. The daily dose units are administered in a method of prophylaxis and/or therapy of endometriosis continuously during a time interval of at least 169 days or 25 weeks, preferably more than two years. The method effectively reduces endometriosis and associated pain, while undesirable side effects including bone density decrease are reduced or eliminated.
62 Citations
24 Claims
- 1. A pharmaceutical preparation for treating endometriosis, said pharmaceutical preparation comprising a daily dose of a gestagen with anti-androgenic activity, which is up to twice that for inhibiting ovulation, and one or more pharmaceutically acceptable aids and/or carriers.
- 11. A kit comprising containing at least 28 daily dose units of a pharmaceutical preparation for treating endometriosis, wherein each of said at least 28 daily dose units comprises a gestagen with anti-androgenic activity at a daily dose that is up to twice that for inhibiting ovulation and one or more pharmaceutically acceptable aids and/or carriers.
- 15. A method of treating endometriosis, said method comprising administering a pharmaceutical preparation containing at least one gestagen with anti-androgenic activity at a daily dose amounting to up to twice that for inhibiting ovulation.
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24. A method of making a pharmaceutical preparation for treating endometriosis, said pharmaceutical preparation comprising a package unit containing at least 28 daily dose units, and wherein each of said daily dose units contains at least one gestagen at a daily doses up to twice that required for inhibiting ovulation and one or more pharmaceutically acceptable aids and/or carriers, and wherein said at least one gestagen is dienogest, cyproterone acetate, or chlormadinone acetate.
Specification