Blood Glucose Monitoring System And Method
First Claim
1. A blood glucose monitoring system comprising:
- at least one fiber optic cable;
a biocompatible sheath enclosing at least part of the at least one fiber optic cable;
sensor material supported at one end of the sheath in optical communication with one end of the at least one fiber optic cable, the sensor material operative for diffracting electromagnetic waves received from the at least one fiber optic cable, the sensor material responsive to changes in an amount of glucose in contact therewith for changing a diffraction of the electromagnetic waves as a function thereof; and
a biocompatible membrane covering the one end of the sheath, the biocompatible membrane in contact with the sensor material and operative for passing to the sensor material glucose from blood in contact with the side of the membrane opposite the sensor material while avoiding the passage of one or more blood proteins to the sensor material.
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Accused Products
Abstract
An optrode for insertion into a blood vessel can include at least one fiber optic, a sheath enclosing at least part of the fiber optic and sensor material in optical communication with one end of the fiber optic. The sensor material is operative for diffracting electromagnetic waves received from the fiber optic and is responsive to changes in an amount of glucose in contact therewith for changing a diffraction of the electromagnetic waves as a function thereof. A membrane covering a distal end of the sheath passes to the sensor material glucose from blood in contact with the side of the membrane opposite the sensor material. Electromagnetic waves input into the fiber optic cable are diffracted by the sensor material. A concentration of glucose in the blood can be estimated from the amount of diffraction of the electromagnetic waves. A signal can be output related to the estimated glucose concentration.
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Citations
17 Claims
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1. A blood glucose monitoring system comprising:
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at least one fiber optic cable; a biocompatible sheath enclosing at least part of the at least one fiber optic cable; sensor material supported at one end of the sheath in optical communication with one end of the at least one fiber optic cable, the sensor material operative for diffracting electromagnetic waves received from the at least one fiber optic cable, the sensor material responsive to changes in an amount of glucose in contact therewith for changing a diffraction of the electromagnetic waves as a function thereof; and a biocompatible membrane covering the one end of the sheath, the biocompatible membrane in contact with the sensor material and operative for passing to the sensor material glucose from blood in contact with the side of the membrane opposite the sensor material while avoiding the passage of one or more blood proteins to the sensor material. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method of measuring blood glucose concentration comprising:
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(a) inserting a vascular access catheter percutaneously into a blood vessel; (b) inserting through the lumen of the catheter and into a flow of blood in the blood vessel at least the distal end of an optrode comprised of at least one fiber optic cable, a biocompatible sheath enclosing at least part of the at least one fiber optic cable, sensor material supported at the distal end of the sheath in optical communication with one end of the at least one fiber optic cable, the sensor material operative for diffracting electromagnetic waves received from the at least one fiber optic cable, the sensor material responsive to changes in an amount of glucose in contact therewith for changing a diffraction of the electromagnetic waves as a function thereof, and a biocompatible membrane covering the distal end of the sheath, the biocompatible membrane in contact with the sensor material and operative for passing to the sensor material glucose from blood in contact with the side of the membrane opposite the sensor material while avoiding the passage of one or more blood proteins to the sensor material; (c) inputting electromagnetic waves into the at least one fiber optic cable; (d) estimating from the diffraction of the electromagnetic waves input in step (c) a concentration of glucose in the blood; and (e) outputting a signal related to the estimate in step (d). - View Dependent Claims (14, 15, 16, 17)
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Specification