Exhaled Breath Condensate Collection and Assay System and Method
First Claim
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1. A method for monitoring a respiratory condition of a subject based on exhaled breath received from the subject, said method comprising:
- continuously or continually collecting exhaled breath condensate (EBC) produced from the subject'"'"'s exhaled breath; and
continually or continuously measuring one or more characteristics of the EBC.
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Abstract
A method and system that provides for minute-to-minute EBC pH monitoring (or for other EBC characteristic monitoring) of a subject that greatly assists in determining the time-course of airway pH changes (or other characteristic changes) in evolving disease processes, and may assist in determining the predictive ability of these tests, as well as determining response to therapy.
100 Citations
99 Claims
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1. A method for monitoring a respiratory condition of a subject based on exhaled breath received from the subject, said method comprising:
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continuously or continually collecting exhaled breath condensate (EBC) produced from the subject'"'"'s exhaled breath; and continually or continuously measuring one or more characteristics of the EBC. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46)
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47. A method for monitoring a respiratory condition of a subject based on exhaled breath received from the subject, said method comprising:
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continuously or continually collecting exhaled breath condensate (EBC) produced from the subject'"'"'s exhaled breath; and continually or continuously measuring PH of the EBC. - View Dependent Claims (48, 49, 50, 51)
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52. A system for monitoring a respiratory condition of a subject, said system comprising:
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an exhaled breath port in communication with a condensate chamber;
said condensate chamber being configured to condense the subject'"'"'s exhaled breath received from said port and produce exhaled breath condensate (EBC);a first collection chamber configured to continuously or continually collect the EBC; a drain off port configured to drain the collected EBC in said first collection chamber as the collected EBC reaches a predetermined volume; and a means for continually or continuously measuring one or more characteristics of the collected EBC. - View Dependent Claims (53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75)
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76. A system for monitoring a respiratory condition of a subject, said system comprising:
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an exhaled breath port in communication with a condensate chamber;
said condensate chamber being configured to condense the subject'"'"'s exhaled breath received from said port and produce exhaled breath condensate (EBC);a first collection chamber configured to continuously collect the EBC; a second collection chamber in fluid communication with said first collection chamber and configured to continuously or continually collect the EBC from the first collection chamber as the first chamber collected EBC reaches a predetermined level in said first collection chamber; a drain off channel configured to drain the collected EBC in said second collection chamber as the collected EBC in said second collection chamber reaches a predetermined volume; and a means for continually or continuously measuring one or more characteristics of the collected EBC. - View Dependent Claims (77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99)
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Specification