Assembly for Filling a Container of a Delivery Device with a Pharmaceutical

• US 20080215030A1
• Filed: 07/31/2006
• Published: 09/04/2008
• Est. Priority Date: 08/08/2005
• Status: Abandoned Application

• Current Assignee: Eli Lilly and Company
• Original Assignee: Eli Lilly and Company
• Inventors: Ritsher, Kenneth Alan
• Application Number:
  US11/997,205
• Publication Number:
  US 20080215030A1
• Time in Patent Office: Days
• US Class Current: 604/413
• CPC Class Codes: A61J 1/062 Carpules
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2013 having two piercing ends
• CPC Class Codes: A61J 1/2051 having tap means, e.g. tap means activated by sliding
• CPC Class Codes: A61J 1/2089 Containers or vials which are to be joined to each other in order to mix their contents combinations of vial and syringe for mixing their contents A61J1/2096

Abstract

A filling assembly for a container of a delivery device. The filling assembly includes a housing, a cartridge, and a transfer needle assembly. The housing is adapted to releaseably secure a fillable secondary container, and to movably mount the pharmaceutical filled cartridge. When the cartridge is advanced within the housing, a needle of the needle assembly pierces a septum of the fillable secondary container, as well as the cartridge septum. Advancement of the cartridge piston, such as with a lever equipped plunging tool of the filling assembly, forces pharmaceutical from the cartridge to the container through the needle.

Claims

1. A filling assembly comprising:

a housing having a first end and a second end spaced in an axial direction, said first end adapted to releaseably secure a fillable secondary container having a septum;

a cartridge mounted within said housing to be movable in said axial direction from a rearward position to a forward position, said cartridge including a body, a movable piston and a septum, said body defining a pharmaceutical filled reservoir sealed at a rearward end by said movable piston and sealed at a forward end by said septum;

a transfer needle assembly including a cannula having a forward tip and a rearward tip, said transfer needle assembly mounted within said housing to be movable in said axial direction from a first needle position to a second needle position by said cartridge moving from said rearward position to said forward position, wherein said transfer needle assembly is sized and configured with said housing to have a first arrangement when in said first needle position and a possible second arrangement when in said second needle position;

wherein said transfer needle assembly, when in said first needle position and in said first arrangement, blocks said cartridge from moving relative to said transfer needle assembly a distance sufficient to cause said rearward tip of said needle to pierce said cartridge septum, whereby said rearward tip is in non-piercing penetrating relationship with the cartridge septum, and further has said forward tip in non-piercing relationship with a septum of a fillable secondary container secured at the first end of said housing; and

wherein said transfer needle assembly, when in said second needle position and in said second arrangement, permits said cartridge to move relative to said transfer needle assembly during movement toward said forward position a distance sufficient to cause said rearward tip of said needle to pierce said cartridge septum and access said pharmaceutical filled reservoir, and has said forward tip in piercing relationship with the septum of a fillable secondary container secured at the first end of said housing for filling the container.

2. The filling assembly of claim 1 wherein said transfer needle assembly includes a needle supporting base and at least one resilient finger extending rearwardly beyond said rearward tip for blocking said cartridge when said transfer needle assembly is in said first needle position and in said first arrangement.

3. The filling assembly of claim 1 wherein said transfer needle assembly includes a projecting tab that engages a complementary opening in said housing to locate said transfer needle assembly.

4. The filling assembly of claim 1 wherein said housing comprises a connecting module structured and arranged to engage a complementary connecting module of the secondary container to secure the container to said housing.

5. The filling assembly of claim 1 wherein said housing comprises a pullable tab, and said connecting module of said housing comprises an opening in said tab.

6. The filling assembly of claim 1 further comprising a plunging tool including a base and a plunger, said base complementarily configured with said housing to axially retain said housing relative to said base, wherein said plunger fits within said cartridge to drivingly engage said cartridge piston, and wherein said plunger and said base are axially movable relative to each other during plunging tool operation.

7. The filling assembly of claim 6 wherein said plunging tool comprises a lever pivotally connected to said base and connected to said plunger such that pivoting of said lever relative to said base drives said plunger into said housing.

8. The filling assembly of claim 6 wherein said housing comprises a cylindrical exterior that nests within a concavity of said base.