LENS CARE SOLUTIONS FOR USE WITH CONTACT LENSES OR CONTACT LENS CASES THAT CONTAIN SILVER

• US 20080218686A1
• Filed: 02/27/2008
• Published: 09/11/2008
• Est. Priority Date: 03/08/2007
• Status: Abandoned Application

• Current Assignee: Bausch & Lomb Incorporated (Bausch Health Cos., Inc.)
• Original Assignee: Bausch & Lomb Incorporated (Bausch Health Cos., Inc.)
• Inventors: Sharma, Ravi, Xia, Erning
• Application Number:
  US12/038,014
• Publication Number:
  US 20080218686A1
• Time in Patent Office: Days
• US Class Current: 351/160R
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/34 Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
• CPC Class Codes: A01N 47/44 Guanidine; Derivatives thereof
• CPC Class Codes: A01N 59/16 Heavy metals; Compounds thereof
• CPC Class Codes: A45C 11/005 Contact lens cases A45C11/046 takes precedence
• CPC Class Codes: A61L 12/086 Container, accessories or devices therefor
• CPC Class Codes: A61L 12/088 Heavy metals
• CPC Class Codes: A61L 12/141 Biguanides, e.g. chlorhexidine
• CPC Class Codes: A61L 12/142 Polymeric biguanides
• CPC Class Codes: A61L 12/145 Polymeric quaternary ammonium compounds
• CPC Class Codes: A61L 2202/122 Chambers for sterilisation
• CPC Class Codes: C11D 3/0078 Compositions for cleaning contact lenses, spectacles or lenses

Abstract

Contact lens care solutions that are formulated for disinfecting or packaging contact lenses that comprise silver, or for disinfecting or storing contact lenses in contact lens cases that comprise silver.

Claims

1. A method of disinfecting or cleaning a contact lens, the method comprising:

positioning a contact lens comprising silver in a lens case or lens package; and

contacting the positioned contact lens with a contact lens solution, wherein the lens solution comprises less than 0.05% w/v chloride ion.

2. The method of claim 1 wherein the silver in the contact lens comprises primarily silver nanoparticles.

3. The method of claim 1 wherein the lens solution comprises less than 0.01% w/v chloride ion.

4. The method of claim 1 wherein the lens solution comprises less than 0.005% w/v chloride ion.

5. The method of claim 1 wherein the lens solution further comprises a cationic antimicrobial component selected from the group consisting of poly(hexamethylene biguanide) or PHMB-CG*, which is present from 0.01 ppm to 3 ppm, α

-[4-tris(2-hydroxyethyl)ammonium chloride-2-butenyl]poly[1-dimethylammonium chloride-2-butenyl]-ω

-tris(2-hydroxyethyl)ammonium chloride, which is present from 1 ppm to 100 ppm, and any mixture thereof.

6. The method of claim 1 wherein the lens solution further comprises dexpanthenol, sorbitol or any mixture thereof.

7. The method of claim 1 wherein the contact lens is a soft, silicon lens.

8. A sealed, contact lens package comprising a contact lens that comprises silver, and a contact lens solution comprising less than 0.05% w/v chloride ion.

9. The lens package of claim 8 wherein the lens solution comprises less than 0.01% w/v chloride ion.

10. The lens package of claim 8 wherein the lens solution comprises less than 0.005% w/v chloride ion.

11. The lens package of claim 8 wherein the silver in the contact lens comprises primarily silver nanoparticles.

12. The lens package of claim 8 wherein the contact lens is a soft, silicon lens.

13. A method of disinfecting or cleaning a contact lens, the method comprising

positioning the contact lens in a lens case that comprises silver;

and

contacting the positioned contact lens with a contact lens solution, wherein the lens solution comprises less than 0.05% w/v chloride ion.

14. The method of claim 13 wherein the lens solution comprises less than 0.01% w/v chloride ion.

15. The method of claim 13 wherein the lens solution comprises less than 0.005% w/v chloride ion.

16. The method of claim 13 wherein the silver in the lens case comprises primarily silver nanoparticles.

17. The method of claim 13 wherein the lens solution further comprises a cationic antimicrobial component selected from the group consisting of poly[dimethylimino-2-butene-1,4-diyl]chloride, α

-[4-tris(2-hydroxyethyl)ammonium chloride-2-butenylpoly[1-dimethylammonium chloride-2-butenyl]-ω

-tris(2-hydroxyethyl) ammonium chloride, myristamidopropyl dimethylamine, benzalkonium halides, alexidine and salts thereof, hexamethylene biguanides and salts thereof and their polymers, and mixtures thereof.

18. The method of claim 13 wherein the contact lens is a soft, silicon lens.