Vascular prosthesis and methods of use

• US 20080221665A1
• Filed: 03/09/2007
• Published: 09/11/2008
• Est. Priority Date: 03/09/2007
• Status: Active Grant

• Current Assignee: NovoStent Corp.
• Original Assignee: NovoStent Corp.
• Inventors: Martin, Gerald Ray, Leopold, Eric W., Hogendijk, Michael, Peckham, John, Parker, Mary Ann
• Granted Patent: US 9,017,395 B2
• Time in Patent Office: Days
• US Class Current: 623/1.22
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2/885 comprising a coil including a plurality of spiral or helical sections with alternate directions around a central axis
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2002/823 Stents, different from stent-grafts, adapted to cover an aneurysm
• CPC Class Codes: A61F 2220/0058 soldered or brazed or welded

Abstract

An implantable vascular prosthesis is provided for use in a wide range of applications wherein at least first and second helical sections having alternating directions of rotation are coupled to one another. The prosthesis is configured to conform to a vessel wall without substantially remodeling the vessel, and permits accurate deployment in a vessel without shifting or foreshortening.

Claims

1. A vascular prosthesis for implantation in a body vessel having a vessel wall, the vascular prosthesis comprising:

an alternating helical section comprising two or more helical portions, wherein a first helical portion has a direction of rotation about a longitudinal axis of the prosthesis opposite to that of a second helical portion, the first and second helical portions are adjoined at a first apex, and the first and second helical portions have different lengths.

2. The vascular prosthesis of claim 1, wherein a helical portion at a first end of the alternating helical section has a different length then the other helical portions.

3. The vascular prosthesis of claim 1, wherein the alternating helical section includes three or more helical portions and the helical portions at the ends of the alternating helical section have lengths that are different from the helical portions between the helical portions at the ends.

4. The vascular prosthesis of claim 1, wherein the alternating helical section includes an even number of helical portions having a first direction of rotation and an odd number of helical portions having a second direction of rotation, wherein the adjoining helical portions define an even number of apices.

5. The vascular prosthesis of claim 1, wherein the first and second helical portions have different pitches.

6. The vascular prosthesis of claim 1, wherein the alternating helical section is capable of assuming a contracted state suitable for transluminal insertion into the body vessel and the distal end of the alternating helical section is configured to be located radially outward when the vascular prosthesis is in the contracted state.

7. The vascular prosthesis of claim 1, wherein the alternating helical section is capable of assuming a contracted state suitable for transluminal insertion into the body vessel and the distal end of the alternating helical section is configured to be located radially inward when the vascular prosthesis is in the contracted state.

8. The vascular prosthesis of claim 1, wherein at least one helical portion is a helical mesh.

9. The vascular prosthesis of claim 1, further comprising a therapeutic agent disposed on a surface of the alternating helical section and the anchor section.

10. The vascular prosthesis of claim 1, further comprising a polymer disposed on a surface of the alternating helical section.

11. The vascular prosthesis of claim 10, wherein the polymer is disposed on a surface of the alternating helical section and configured to be a stent graft.

12. The vascular prosthesis of claim 10, wherein the polymer is configured to elute a therapeutic agent.

13. The vascular prosthesis of claim 1, further comprising a radially expanding anchor section joined to a first end of the alternating helical section.

14. The vascular prosthesis of claim 13, wherein the alternating helical section and the first anchor section each are capable of assuming a contracted state suitable for transluminal insertion into the body vessel and a deployed state wherein the helical section and first anchor section are configured to engage the vessel wall.

15. The vascular prosthesis of claim 1, wherein the alternating helical section comprises a shape memory material.

16. The vascular prosthesis of claim 15, wherein the shape memory material is a nickel titanium alloy.

17. The vascular prosthesis of claim 13, wherein the alternating helical section and the anchor section are separately formed and then coupled together.

18. The vascular prosthesis of claim 13, wherein the alternating helical section and the anchor section are integrally formed.

19. A vascular prosthesis for implantation in a body vessel having a vessel wall, the vascular prosthesis comprising:

an alternating helical section comprising at least first and second helical portions, wherein the first helical portion has a direction of rotation about a longitudinal axis of the prosthesis opposite to that of the second helical portion, the first and second helical portions are coupled at a first apex, and the first helical portion has a pitch that is different than a pitch of the second helical portion.

20. The vascular prosthesis of claim 19, wherein the alternating helical section includes an even number of helical portions having a first direction of rotation and an odd number of helical portions having a second direction of rotation.

21. The vascular prosthesis of claim 19, wherein the alternating helical section comprises a shape memory material.

22. The vascular prosthesis of claim 21, wherein the shape memory material is a nickel titanium alloy.

23. The vascular prosthesis of claim 19 further comprising a radially self-expanding anchor section joined to an end of the alternating helical section.

24. The vascular prosthesis of claim 23, wherein the alternating helical section and the anchor section are separately formed and then coupled together.

25. The vascular prosthesis of claim 19, wherein the alternating helical section is capable of assuming a contracted state suitable for transluminal insertion into the body vessel and the distal end of the alternating helical section is configured to be located radially outward when the vascular prosthesis is in the contracted state.