APPARATUS FOR SUPPORTING DIAGNOSIS OF CANCER

• US 20080227183A1
• Filed: 03/13/2008
• Published: 09/18/2008
• Est. Priority Date: 03/14/2007
• Status: Abandoned Application

• Current Assignee: Sysmex Corporation
• Original Assignee: Sysmex Corporation
• Inventors: Kouchi, Yasuhiro, Ishihara, Hideki
• Application Number:
  US12/048,103
• Publication Number:
  US 20080227183A1
• Time in Patent Office: Days
• US Class Current: 435/287.1
• CPC Class Codes: G01N 2333/912 transferring phosphorus containing groups, e.g. kinases (2.7)
• CPC Class Codes: G01N 33/574 for cancer
• CPC Class Codes: G01N 35/0099 comprising robots or similar manipulators robots per se B25J
• CPC Class Codes: G01N 35/109 with two horizontal degrees of freedom

Abstract

A cancer diagnosis supporting apparatus is provided with a memory for storing a predetermined reference value, a diagnosis support information preparer for preparing the diagnosis support information of cancer by comparing a measurement value obtained from a malignant tumor collected from a cancer patient and the reference value, and a change acceptor for accepting change of the reference value and for storing the changed reference value in the memory.

Claims

1. An apparatus for supporting diagnosis of cancer, comprising:

a memory for storing a predetermined reference value;

a measurement value acquirer for acquiring a measurement value of a predetermined item from a malignant tumor collected from a cancer patient;

a diagnosis support information preparer for preparing the diagnosis support information of cancer by comparing the acquired measurement value and the reference value; and

a change acceptor for accepting change of the reference value and for storing the changed reference value in the memory.

2. The apparatus of claim 1, wherein the diagnosis support information preparer prepares the diagnosis support information by comparing the acquired measurement value and the changed reference value after the changed reference value has been stored in the memory.

3. The apparatus of claim 1, comprising a display and a display controller for displaying the obtained diagnosis support information on the display.

4. The apparatus of claim 3, wherein the display controller displays a reference value changing screen for inputting the change of the reference value on the display, and the change acceptor accepts the input change of the reference value.

5. The apparatus of claim 4, wherein the display controller displays a graph representing a disease free survival on the reference value changing screen.

6. The apparatus of claim 3, wherein the memory stores a plurality of sample data, each of the sample data has a measurement value of the predetermined item of a cancer patient and clinical information of the cancer patient after extirpation of the malignant tumor, and the measurement value and the clinical information are associated with each other.

7. The apparatus of claim 6, wherein the display controller displays a screen including a sample data distribution chart based on the plurality of measurement values and the plurality of clinical information stored in the memory.

8. The apparatus of claim 7, wherein the display controller displays the screen including the sample data distribution chart which displays the reference value as a line movable on the sample data distribution chart;

and

the change acceptor accepts change of the reference value by accepting movement of the line of the reference value on the sample data distribution chart.

9. The apparatus of claim 6, further comprising a data change acceptor for accepting change of the clinical information of the sample data stored in the memory, wherein the display controller displays a sample data updating screen for inputting the change of the clinical information on the display, and the data change acceptor accepts the input change of the clinical information.

10. The apparatus of claim 6, further comprising a data adder for adding sample data of a cancer patient to the memory.

11. The apparatus of claim 1, wherein the clinical information is at least one selected from a group consisting of presence or absence of recurrence, anticancer drug sensitivity, and survival rate.

12. The apparatus of claim 1, wherein the predetermined item includes item related to an expression and/or item related to activity of a cell cycle protein contained in the malignant tumor.

13. The apparatus of claim 12, wherein the predetermined item includes a specific activity of the cell cycle protein.

14. The apparatus of claim 1, wherein the diagnosis support information of the cancer is anticancer drug sensitivity or recurrence risk after extirpation of the malignant tumor of the cancer patient.

15. An apparatus for supporting diagnosis of cancer, comprising:

a memory for storing a predetermined reference value;

a measuring unit for measuring a malignant tumor collected from a cancer patient;

a measurement value obtainer for obtaining a measurement value of a predetermined item from the malignant tumor;

a diagnosis support information preparer for preparing the diagnosis support information of cancer by comparing the acquired measurement value and the reference value;

a display;

a display controller for displaying the obtained diagnosis support information on the display; and

a change acceptor for accepting change of the reference value and for storing the changed reference value in the memory.

16. The apparatus of claim 15, wherein the measuring unit comprises:

an activity measuring unit for measuring each activity value of a first cyclin-dependent kinase (first CDK) and a second cyclin-dependent kinase (second CDK) from the malignant tumor; and

an expression level measuring unit for measuring each expression level of the first CDK and the second CDK from the malignant tumor;

wherein the measurement value obtainer obtains a first specific activity of the first CDK based on the measurement results of the activity measuring unit and the expression level measuring unit, a second specific activity of the second CDK based on the measurement results of the activity measuring unit and the expression level measuring unit, and a specific activity ratio of the first specific activity and the second specific activity;

wherein preparer for preparing the diagnosis support information of cancer by comparing the obtained specific activity ratio and the reference value stored in the memory.

17. An apparatus for supporting diagnosis of cancer, comprising:

a memory means for storing a predetermined reference value;

a measurement value acquiring means for acquiring a measurement value of a predetermined item from a malignant tumor collected from a cancer patient;

a diagnosis support information preparing means for preparing the diagnosis support information of cancer by comparing the acquired measurement value and the reference value; and

a change accepting means for accepting change of the reference value and for storing the changed reference value in the memory means.

18. The apparatus of claim 17, wherein the diagnosis support information preparing means prepares the diagnosis support information by comparing the acquired measurement value and the changed reference value after the changed reference value has been stored in the memory means.

19. The apparatus of claim 17, comprising a display means and a display controlling means for displaying the obtained diagnosis support information on the display means.

20. The apparatus of claim 19, wherein the display controlling means displays a reference value changing screen for inputting the change of the reference value on the display means, and the change accepting means accepts the input change of the reference value.