INTRALUMENAL MATERIAL REMOVAL USING A CUTTING DEVICE FOR DIFFERENTIAL CUTTING

• US 20080228208A1
• Filed: 03/18/2008
• Published: 09/18/2008
• Est. Priority Date: 03/10/2003
• Status: Abandoned Application

• Current Assignee: Pathway Medical Technologies, Inc. (Bayer AG)
• Original Assignee: Pathway Medical Technologies, Inc. (Bayer AG)
• Inventors: WULFMAN, Edward I., TORRANCE, Casey, YOUMANS, Scott, NISTAL, Brent
• Application Number:
  US12/050,833
• Publication Number:
  US 20080228208A1
• Time in Patent Office: Days
• US Class Current: 606/159
• CPC Class Codes: A61B 17/32002 with continuously rotating, oscillating or reciprocating cutting instruments
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 17/320758 with a rotating cutting instrument, e.g. motor driven A61B17/320725, A61B17/32075 and A61B17/320783 take precedence; for removing intra-ocular material A61F9/00763; endoscopic rotatable cutting instruments A61B17/32002
• CPC Class Codes: A61B 17/3462 with means for changing the diameter or the orientation of the entrance port of the cannula, e.g. for use with different-sized instruments, reduction ports, adapter seals expandable cannulas A61B17/3417
• CPC Class Codes: A61B 2017/00017 Electrical control of surgical instruments
• CPC Class Codes: A61B 2017/00199 with a console, e.g. a control panel with a display
• CPC Class Codes: A61B 2017/00973 pedal-operated
• CPC Class Codes: A61B 2017/22049 Means for locking the guide wire in the catheter
• CPC Class Codes: A61B 2017/2927 the angular position of the head being adjustable with respect to the shaft
• CPC Class Codes: A61B 2017/320032 Details of the rotating or oscillating shaft, e.g. using a flexible shaft
• CPC Class Codes: A61B 2217/005 with suction drainage system
• CPC Class Codes: A61B 5/061 Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body A61B1/00158 takes precedence
• CPC Class Codes: A61B 5/415 the glands, e.g. tonsils, adenoids or thymus
• CPC Class Codes: A61B 5/418 lymph vessels, ducts or nodes
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/4209 by using holders, e.g. positioning frames
• CPC Class Codes: A61M 2039/062 used with a catheter
• CPC Class Codes: A61M 25/0147 with movable mechanical means, e.g. pull wires
• CPC Class Codes: A61M 39/06 Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
• CPC Class Codes: A61M 39/0606 without means for adjusting the seal opening or pressure A61M39/0693 takes precedence

Abstract

Intralumenal material removal systems are provided using an advanceable and rotatable cutter assembly designed for differential cutting. The intralumenal material removal system includes a cutter assembly positionable in the body cavity of a mammalian subject. One embodiment of the cutter assembly comprises a cutter with blades that are designed and arranged to form an acute blade angle of attack with the matter-to-be-removed. The cutter assembly is axially advanceable by translating the drive shaft and rotatable by rotating the drive shaft. The occlusive material is scraped by the cutter assembly and may be aspirated to remove the material from the body cavity. The cutter assembly may provide aspiration ports positioned between facing surfaces of the blades.

Claims

1. An intralumenal material removal system comprising:

a rotatable drive shaft and a drive system operably coupled to the drive shaft for rotating the drive shaft;

a cutter assembly coupled to the drive shaft for rotation with the drive shaft, the cutter assembly having a plurality of differential cutting blades, each differential cutting blade having an acute angle of attack formed as an angle between the leading face of the blade and a tangent to a circle formed by the circumference of the cutter assembly of greater than 30° and

less than 90°

;

a catheter forming a sealed lumen with the cutter assembly;

an aspiration component in proximity to the cutter assembly; and

an infusion system providing infusion of liquid in proximity to the cutter assembly.

2. The system of claim 1, wherein the acute angle of attack formed as an angle between the leading face of the blade and a tangent to a circle formed by the circumference of the cutter assembly is between about 45°

and 75°

.

3. The system of claim 1, wherein the acute angle of attack formed as an angle between the leading face of the blade and a tangent to a circle formed by the circumference of the cutter assembly is greater than about 60°

and less than 90°

.

4. The system of claim 1, wherein the cutting blades are raised cutting flutes provided on a fixed diameter cutter assembly.

5. The system of claim 1, wherein the cutting blades are provided as cutting members of an expandable cutter assembly.

6. The system of claim 1, additionally comprising a control unit designed to remain outside the body during a material removal operation, the control unit having an advancer system for axially displacing the rotating cutter assembly drive shaft and cutter assembly relative to the control unit.

7. The system of claim 1, additionally comprising an automated guidewire braking system that is automatically actuated to brake during activation of the cutter assembly drive system, thereby releasably restricting axial and rotational movement of a guidewire.

8. The system of claim 1, wherein the drive system is unidirectional and capable of rotating the cutter assembly at variable speeds ranging from 500 rpm to 150,000 rpm.

9. The system of claim 1, wherein the drive system is bidirectional and capable of rotating the drive shaft selectively in both a clockwise and a counterclockwise direction.

10. The system of claim 1, wherein the differential cutting blades have an abrasive surface.

11. The system of claim 1, wherein the differential cutting blades are chamfered at least one of their proximal and distal ends.

12. The system of claim 1, wherein the differential cutting blades are constructed from a material selected from the group consisting of:

a stainless steel;

vanadium steel;

nickel-titanium;

titanium-containing metals, and oxide ceramics.

13. The system of claim 1, wherein the differential cutting blades have an asymmetrical curved profile.

14. The system of claim 1, wherein the differential cutting blades have a symmetrical curved profile.

15. An intralumenal material removal system comprising:

a rotatable drive shaft and a drive system operably coupled to the drive shaft for rotating the drive shaft;

a sealed lumen formed between the rotatable drive shaft and a catheter;

a cutter assembly coupled to the drive shaft for rotation with the drive shaft, the cutter assembly having at least one differential cutting blade having an acute angle of attack formed as an angle between the leading face of the blade and a tangent to a circle formed by the circumference of the cutter assembly of greater than 30° and

less than 90°

; and

an aspiration source providing aspiration through at least one material removal port in proximity to the cutter assembly and withdrawal of material through the sealed lumen.

16. The intralumenal material removal system of claim 15, wherein the acute angle of attack formed as an angle between the leading face of the blade and a tangent to a circle formed by the circumference of the cutter assembly is greater than about 60°

and less than 90°

.

17. The intralumenal material removal system of claim 15, wherein the cutter assembly comprises multiple cutting members having different cutting characteristics.

18. An intralumenal material removal system comprising:

a rotatable drive shaft and a drive system operably coupled to the drive shaft for rotating the drive shaft;

a sealed lumen formed between the rotatable drive shaft and a catheter;

a cutter assembly coupled to the drive shaft for rotation with the drive shaft, the cutter assembly having at least one differential cutting blade having an acute angle of attack formed as an angle between the leading face of the blade and a tangent to a circle formed by the circumference of the cutter assembly of greater than 30° and

less than 90°

; and

a liquid infusion system providing infusion of liquid in proximity to the cutter assembly.

19. The intralumenal material removal system of claim 18, wherein the acute angle of attack formed as an angle between the leading face of the blade and a tangent to a circle formed by the circumference of the cutter assembly is greater than about 60°

and less than 90°

.

20. The intralumenal material removal system of claim 18, additionally comprising a control unit provided as a separate console incorporating displays for providing information concerning operating conditions and feedback from the material removal site to the operator.