ENDOVASCULAR DEVICES AND METHODS TO PROTECT ANEURYSMAL WALL
First Claim
1. A system to protect the wall of an aneurysm in a vessel wherein the system comprises:
- a liner comprising one or more chambers, said one or more chambers comprising hardening agent, wherein said liner is configured to conform to the interior surface of the aneurysm following introduction of said liner into the vessel, and wherein said hardening agent being activated by body environment to become stiff.
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Abstract
Methods and systems for preventing aneurysm rupture and reducing the risk of migration and endoleak are disclosed. Specifically, a hardenable liner is applied directly to treat the interior of the aneurysm site. The hardening agent remains flexible in the pliable mode so that the liner can be collapsed and compressed in a delivery catheter. After deploying in the aneurysm, the flexible liner expands by the hemodynamic force and conforms to the inner surface of the aneurysm. While the liner is still conforming to the aneurysm, the hardening agent in the liner is activated by the body environment and becomes stiff. The liner is thus transformed from the pliable mode to the strengthening mode and providing support for the aneurysm wall. Also disclosed are methods to deliver the hardenable liner directly to treatment sites.
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Citations
19 Claims
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1. A system to protect the wall of an aneurysm in a vessel wherein the system comprises:
a liner comprising one or more chambers, said one or more chambers comprising hardening agent, wherein said liner is configured to conform to the interior surface of the aneurysm following introduction of said liner into the vessel, and wherein said hardening agent being activated by body environment to become stiff. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. An endovascular system to protect aneurysm wall comprising:
a hardenable liner having an inner wall and an outer wall and a hardening agent encapsulated between walls, said hardenable liner having a first configuration and a second configuration, said first configuration being low profile delivery configuration and insertable into blood vessel, said second configuration being defined by the blood vessel, said hardenable liner being expandable plastically from said first configuration to said second configuration by the hemodynamic force in said blood vessel, said hardenable liner having at least one wall being permeable to moisture, said hardening agent being activated by said moisture to become stiff.
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19. A method of treatment of an aneurysm comprising:
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providing an hardenable liner comprising one or more chambers and hardening agent; and anchoring a portion of the hardenable liner in the vessel adjacent the aneurysm with a first expandable element; and introducing hemodynamic force in the hardenable liner whereby said liner expands and conforms to the interior surface of the aneurysm; and providing and deploying a second expandable element to open the flow conduit at the junction between said hardenable liner and the vessel; and introducing body fluid into the one or more chambers whereby said hardening agent is stiffened and protects the vessel.
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Specification