Identifying Co-associating Bioattributes
First Claim
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1. A bioinformatics method for identifying combinations of pangenetic and non-pangenetic attributes that co-associate with a query attribute, comprising:
- a) receiving a query attribute;
b) accessing a set containing attribute combinations and frequencies of occurrence of the attribute combinations for a set of attribute profiles associated with a group of query-attribute-positive individuals and for a set of attribute profiles associated with a group of query-attribute-negative individuals, wherein each of the attribute combinations contains at least one pangenetic attribute and at least one non-pangenetic attribute;
c) identifying, based on the frequencies of occurrence, attribute combinations that co-associate with the query attribute; and
d) transmitting at least one of the identified attribute combinations as output to indicate combinations of pangenetic and non-pangenetic attributes that co-associate with the query attribute.
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Abstract
A bioinformatics method, software, database and system are presented in which combinations of bioattributes comprising pangenetic and non-pangenetic attributes that co-associate with a query attribute (i.e., an attribute of interest) are identified from a database containing attribute combinations and corresponding frequencies of occurrence of each of the attribute combinations for a group of query-attribute-positive individuals and for a group of query-attribute-negative individuals.
91 Citations
20 Claims
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1. A bioinformatics method for identifying combinations of pangenetic and non-pangenetic attributes that co-associate with a query attribute, comprising:
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a) receiving a query attribute; b) accessing a set containing attribute combinations and frequencies of occurrence of the attribute combinations for a set of attribute profiles associated with a group of query-attribute-positive individuals and for a set of attribute profiles associated with a group of query-attribute-negative individuals, wherein each of the attribute combinations contains at least one pangenetic attribute and at least one non-pangenetic attribute; c) identifying, based on the frequencies of occurrence, attribute combinations that co-associate with the query attribute; and d) transmitting at least one of the identified attribute combinations as output to indicate combinations of pangenetic and non-pangenetic attributes that co-associate with the query attribute. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A program storage device readable by a machine and containing a set of instructions which, when read by the machine, causes execution of a bioinformatics method for identifying combinations of pangenetic and non-pangenetic attributes that co-associate with a query attribute, comprising:
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a) receiving a query attribute; b) accessing a set containing attribute combinations and frequencies of occurrence of the attribute combinations for a set of attribute profiles associated with a group of query-attribute-positive individuals and for a set of attribute profiles associated with a group of query-attribute-negative individuals, wherein each of the attribute combinations contains at least one pangenetic attribute and at least one non-pangenetic attribute; c) identifying, based on the frequencies of occurrence, attribute combinations that co-associate with the query attribute; and d) transmitting at least one of the identified attribute combinations as output to indicate combinations of pangenetic and non-pangenetic attributes that co-associate with the query attribute. - View Dependent Claims (13, 14)
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15. A bioinformatics database system for identifying combinations of pangenetic and non-pangenetic attributes that co-associate with a query attribute, comprising:
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a) a memory containing; i) a first data structure containing attribute combinations and frequencies of occurrence of the attribute combinations for a set of attribute profiles associated with a group of query-attribute-positive individuals and for a set of attribute profiles associated with a group of query-attribute-negative individuals, wherein each of the attribute combinations contains at least one pangenetic attribute and at least one non-pangenetic attribute; b) a processor for; i) receiving the query attribute; ii) accessing the first data structure; iii) identifying, based on the frequencies of occurrence, attribute combinations contained in the first data structure that co-associate with the query attribute; and iv) transmitting at least one of the identified attribute combinations as output to indicate combinations of pangenetic and non-pangenetic attributes that co-associate with the query attribute. - View Dependent Claims (16, 17)
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18. A bioinformatics computer-based system for identifying combinations of pangenetic and non-pangenetic attributes that co-associate with a query attribute, comprising:
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a) a first data communications subsystem for receiving a query attribute; b) a data accessing subsystem for accessing a set containing attribute combinations and frequencies of occurrence of the attribute combinations for a set of attribute profiles associated with a group of query-attribute-positive individuals and for a set of attribute profiles associated with a group of query-attribute-negative individuals, wherein each of the attribute combinations contains at least one pangenetic attribute and at least one non-pangenetic attribute; c) a data processing subsystem for identifying, based on the frequencies of occurrence, attribute combinations that co-associate with the query attribute; and d) a second data communications subsystem for transmitting at least one of the identified attribute combinations as output to indicate combinations of pangenetic and non-pangenetic attributes that co-associate with the query attribute. - View Dependent Claims (19, 20)
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Specification