Lifestyle Optimization and Behavior Modification

• US 20080228735A1
• Filed: 03/15/2008
• Published: 09/18/2008
• Est. Priority Date: 03/16/2007
• Status: Active Grant

• Current Assignee: 23andme Incorporated (23andMe Holding Co.)
• Original Assignee: Expanse Networks, Inc.
• Inventors: Eldering, Charles Anthony, Kenedy, Andrew Alexander
• Granted Patent: US 8,606,761 B2
• Time in Patent Office: Days
• US Class Current: 707/3
• CPC Class Codes: G06F 16/00 Information retrieval; Database structures therefor; File system structures therefor
• CPC Class Codes: G06F 16/2282 Tablespace storage structures; Management thereof
• CPC Class Codes: G06F 16/24575 using context
• CPC Class Codes: G06F 16/24578 using ranking
• CPC Class Codes: G06F 16/285 Clustering or classification
• CPC Class Codes: G06F 16/951 Indexing; Web crawling techniques
• CPC Class Codes: G06F 16/9535 Search customisation based on user profiles and personalisation
• CPC Class Codes: G06F 16/9538 Presentation of query results
• CPC Class Codes: G06F 16/955 using information identifiers, e.g. uniform resource locators [URL]
• CPC Class Codes: G06N 3/08 Learning methods
• CPC Class Codes: G06N 5/04 Inference or reasoning models
• CPC Class Codes: G06N 7/01 Probabilistic graphical models, e.g. probabilistic networks
• CPC Class Codes: G06Q 40/00 Finance; Insurance; Tax strategies; Processing of corporate or income taxes
• CPC Class Codes: G06Q 40/08 Insurance
• CPC Class Codes: G09B 19/00 Teaching not covered by other main groups of this subclass teaching or practice apparatus for gun-aiming or gun-laying F41G3/26
• CPC Class Codes: G16B 20/00 ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
• CPC Class Codes: G16B 20/20 Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
• CPC Class Codes: G16B 20/40 Population genetics; Linkage disequilibrium
• CPC Class Codes: G16H 20/30 relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 50/30 : for calculating health indices; for individual health risk assessment
• CPC Class Codes: G16H 50/70 : for mining of medical data, e.g. analysing previous cases of other patients
• CPC Class Codes: G16H 70/20 : relating to practices or guidelines
• CPC Class Codes: H04L 67/306 : User profiles

Abstract

A method, software, database and system for determining an approach to achieve a desired lifestyle, behavioral disposition, and genetic based predisposition for an individual are presented in which an attribute profile of the individual containing genetic and non-genetic attributes is compared against a database containing combinations of genetic and non-genetic attributes that are statistically associated with relevant desirable or undesirable attributes derived from other individuals.

Claims

1. A computer based method for determining an approach to achieve a desired lifestyle for an individual, comprising:

a) receiving a query for determining an approach to achieve a desired lifestyle for an individual;

b) accessing an attribute profile associated with the individual, the attribute profile comprising pangenetic and non-pangenetic attributes;

c) accessing a database containing a set of attribute combinations that are statistically associated with a set of desired lifestyle attributes, wherein each of the attribute combinations contains at least one pangenetic attribute and at least one non-pangenetic attribute;

d) determining one or more approaches to achieve the desired lifestyle for the individual based on at least one comparison of the attribute profile with the set of attribute combinations; and

e) transmitting the determination as output.

2. The computer based method of claim 1, wherein the transmitting in step (e) is to at least one destination selected from the group consisting of a user, a database, a dataset, a computer readable memory, a computer readable medium, a computer processor, a computer network, a printout device, a visual display, and a wireless receiver.

3. The computer based method of claim 1, wherein the determination transmitted as output comprises one or more modifiable attributes associated with a corresponding potential for achieving the desired lifestyle that is greater than or equal to a user specified threshold.

4. The computer based method of claim 1, wherein the database also contains corresponding statistical results which indicate the strength of association of each of the attribute combinations with one or more of the desired lifestyle attributes.

5. The computer based method of claim 4, wherein step (e) further comprises transmitting at least a portion of the corresponding statistical results as output to indicate the individual'"'"'s potential for achieving the desired lifestyle using the one or more approaches determined.

6. The computer based method of claim 4, wherein step (e) further comprises transmitting at least one of the corresponding statistical results as output to indicate the individual'"'"'s potential for achieving the desired lifestyle without using the one or more approaches determined.

7. The computer based method of claim 4, wherein step (d) further comprises identifying, from the set of attribute combinations, at least one attribute combination containing one or more pangenetic attributes which occur in the attribute profile and one or more modifiable attributes which do not occur in the attribute profile, and wherein step (e) further comprises transmitting the modifiable attributes as output.

8. The bioinformatics method of claim 7, wherein the database also contains corresponding statistical results which indicate the strength of association of each of the attribute combinations with one or more of the desired lifestyle attributes, and wherein step (d) further comprises:

i) identifying how many of the desired lifestyle attributes are associated with each of the modifiable attributes; and

ii) generating a tabulation containing the modifiable attributes rank-ordered based on the corresponding statistical results and on how many of the desired lifestyle attributes are associated with each of the modifiable attributes, to indicate which of the modifiable attributes have the largest influence on the individual'"'"'s potential for achieving the desired lifestyle.

9. The computer based method of claim 1, further comprising:

f) associating the output with the individual and storing the association.

10. The computer based method of claim 1, wherein the identity of the individual is masked or anonymized.

11. The computer based method of claim 1, wherein each of the attribute combinations contains at least one pangenetic attribute, at least one physical attribute, at least one behavioral attribute, and at least one situational attribute.

12. A computer based method for determining an approach to achieve a desired lifestyle for an individual, comprising:

a) receiving a query for determining an approach to achieve a desired lifestyle for an individual;

b) accessing an attribute profile associated with the individual, the attribute profile comprising pangenetic and non-pangenetic attributes;

c) accessing a database containing a set of attribute combinations that are statistically associated with a set of desired lifestyle attributes in other individuals, wherein each of the attribute combinations contains at least one pangenetic attribute and at least one non-pangenetic attribute;

d) identifying, from the set of attribute combinations, at least one attribute combination containing one or more pangenetic attributes which occur in the attribute profile and one or more modifiable attributes which do not occur in the attribute profile; and

e) transmitting the modifiable attributes as output to provide a determination of one or more approaches to achieve the desired lifestyle for the individual.

13. The computer based method of claim 12, wherein the database also contains corresponding statistical results which indicate the strength of association of each of the attribute combinations with one or more of the desired lifestyle attributes, and wherein step (e) further comprises transmitting at least a portion of the corresponding statistical results as output to indicate the individual'"'"'s potential for achieving the desired lifestyle using the one or more approaches determined.

14. A database system for determining an approach to achieve a desired lifestyle for an individual, comprising:

a) a memory containing;

i) a first data structure containing an attribute profile associated with the individual, the attribute profile comprising pangenetic and non-pangenetic attributes;

ii) a second data structure containing a database which contains a set of attribute combinations that are statistically associated with a set of desired lifestyle attributes, wherein each of the attribute combinations contains at least one pangenetic attribute and at least one non-pangenetic attribute;

b) a processor for;

i) receiving a query for determining an approach to achieve a desired lifestyle for an individual;

ii) accessing the first data structure;

iii) accessing the second data structure;

iv) determining one or more approaches to achieve the desired lifestyle for the individual based on at least one comparison of the attribute profile contained in the first data structure with the set of attribute combinations contained in the second data structure; and

v) transmitting the determination as output.

15. The database system of claim 14, wherein part (iv) further comprises identifying, from the set of attribute combinations, at least one attribute combination containing one or more pangenetic attributes which occur in the attribute profile and one or more modifiable attributes which do not occur in the attribute profile, and wherein part (v) further comprises transmitting the modifiable attributes as output.

16. A program storage device readable by a machine and containing a set of instructions which, when read by the machine, causes execution of a computer based method for determining an approach to achieve a desired lifestyle for an individual, comprising:

a) receiving a query for determining an approach to achieve a desired lifestyle for an individual;

b) accessing an attribute profile associated with the individual, the attribute profile comprising pangenetic and non-pangenetic attributes;

c) accessing a database containing a set of attribute combinations that are statistically associated with a set of desired lifestyle attributes, wherein each of the attribute combinations contains at least one pangenetic attribute and at least one non-pangenetic attribute;

d) determining one or more approaches to achieve the desired lifestyle for the individual based on at least one comparison of the attribute profile with the set of attribute combinations; and

e) transmitting the determination as output.

17. The program storage device of claim 16, wherein step (d) further comprises identifying, from the set of attribute combinations, at least one attribute combination containing one or more pangenetic attributes which occur in the attribute profile and one or more modifiable attributes which do not occur in the attribute profile, and wherein step (e) further comprises transmitting the modifiable attributes as output.

18. A computer based method for determining an approach to achieve a desired behavioral disposition of an individual, comprising:

a) receiving a query for determining an approach to achieve a desired behavioral disposition of an individual;

b) accessing an attribute profile associated with the individual, the attribute profile comprising pangenetic and non-pangenetic attributes;

c) accessing a database containing a set of attribute combinations that are statistically associated with a set of desired behavioral attributes, wherein each of the attribute combinations contains at least one pangenetic attribute and at least one non-pangenetic attribute;

d) determining one or more approaches to achieve the desired behavioral disposition of the individual, based on at least one comparison of the attribute profile with the set of attribute combinations; and

e) transmitting the determination as output.

19. The computer based method of claim 18, wherein step (d) further comprises identifying, from the set of attribute combinations, at least one attribute combination containing one or more pangenetic attributes which occur in the attribute profile and one or more modifiable attributes which do not occur in the attribute profile, and wherein step (e) further comprises transmitting the modifiable attributes as output to indicate attributes that can be modified as an approach to achieve a desired behavioral disposition of the individual.

20. A computer based method for determining genetic based counseling for an individual, comprising:

a) receiving a query for determining genetic based counseling for an individual;

b) accessing an attribute profile associated with the individual, the attribute profile comprising pangenetic and non-pangenetic attributes;

c) accessing a database containing a set of attribute combinations that are statistically associated with a set of desirable and undesirable non-pangenetic attributes, wherein each of the attribute combinations contains at least one pangenetic attribute and at least one non-pangenetic attribute;

d) determining genetic based counseling for the individual based on at least one comparison of the attribute profile with the set of attribute combinations; and

e) transmitting the determination as output.

21. The computer based method of claim 20, wherein the database also contains corresponding statistical results which indicate the strength of association of each of the attribute combinations with one or more of the desirable and undesirable non-pangenetic attributes, wherein step (d) further comprises identifying attribute combinations from the database which contain attributes that also occur in the attribute profile associated with the individual, and wherein step (e) further comprises transmitting modifiable attributes from one or more of the identified attribute combinations and at least a portion of the corresponding statistical results as output to determine genetic based counseling for the individual which indicates modifiable attributes that can increase the individual'"'"'s predisposition for one or more of the desirable non-pangenetic attributes and modifiable attributes that can decrease the individual'"'"'s predisposition for one or more of the undesirable non-pangenetic attributes.