Analyzing Body Tissue

• US 20080234942A1
• Filed: 06/27/2005
• Published: 09/25/2008
• Est. Priority Date: 06/25/2004
• Status: Abandoned Application

• Current Assignee: Tissuomics Limited
• Original Assignee: Tissuomics Limited
• Inventors: Gaved, Matthew, Farquharson, Michael
• Application Number:
  US11/630,251
• Publication Number:
  US 20080234942A1
• Time in Patent Office: Days
• US Class Current: 702/19
• CPC Class Codes: G01N 2223/306 computer control
• CPC Class Codes: G01N 2223/6126 tissue
• CPC Class Codes: G01N 23/20083 by using a combination of at least two measurements at least one being a transmission measurement and one a scatter measurement

Abstract

The invention describes a method for analysing a body tissue sample, the method comprising irradiating the tissue sample (4) with penetrating radiation and detecting transmitted, (14) and/or scattered radiation (16, 18) from the sample, wherein the duration of the analysis is determined from one or more desired confidence levels based on a model or algorithm defining a relationship between analysis duration and confidence level. The invention also describes apparatus for implementing the method and computer software for controlling the apparatus.

Claims

1-13. -13. (canceled)

14. A method for analysing a body tissue sample, the method comprising irradiating the tissue sample with penetrating radiation and detecting transmitted or scattered radiation from the sample, wherein the duration of the analysis is determined from one or more desired confidence levels based on a model or algorithm defining a relationship between analysis duration and confidence level.

15. A method according to claim 14, wherein the one or more desired confidence levels are operator selected.

16. A method according to claim 14, wherein the one or more desired confidence levels are automatically set.

17. A method according to claim 14, wherein the one or more desired confidence levels operate as a function of both an operator selection and an automatic setting.

18. A method according to claim 14, wherein the determination of duration is a one-off calculation at the start of the analysis procedure.

19. A method according to claim 14, wherein the determination of duration is a one-off calculation at a predetermined point in the procedure.

20. A method according to claim 14, wherein the determination of duration is adjusted dynamically as the analysis progresses.

21. A method according to claim 14, wherein the determination of duration is adjusted or updated at least twice during the course of the analysis.

22. A method according to claim 14, wherein the model or algorithm is configured to take into account of one or more factors.

23. A method according to claim 22, wherein the one or more factors comprise:

histopathology data or histopathological diagnosis;

tissue characteristics/types;

patient information;

or other tissue information.

24. A method for creating or updating a model(s) or an algorithm(s) defining a relationship between analysis duration and confidence level for use in the method of claim 14, wherein the model(s) or algorithm(s) are derived empirically, based on measurements from tissue samples exhibiting a variety of factors.

27. A method according to claim 15, wherein the determination of duration is a one-off calculation at the start of the analysis procedure.

28. A method according to claim 16, wherein the determination of duration is a one-off calculation at the start of the analysis procedure.

29. A method according to claim 17, wherein the determination of duration is a one-off calculation at the start of the analysis procedure.

25. Tissue analysis apparatus for analysing a biological tissue sample, wherein the apparatus comprises a source of penetrating radiation and at least one detector for detecting transmitted or scattered radiation, in use, by a biological sample, and wherein said detector(s) is in communication with a processor that is configured to determine the duration of the analysis of the sample from one or more desired confidence levels based on a model or algorithm defining a relationship between analysis duration and confidence level.

26. Computer software for analysing a biological tissue sample, wherein said software is operative to allow a processor to determine the duration of the analysis of the sample being exposed to a source of radiation based on one or more desired confidence levels based on a model or algorithm defining a relationship between analysis duration and confidence level.