Device for the delivery of viscous compositions

• US 20080243130A1
• Filed: 03/28/2008
• Published: 10/02/2008
• Est. Priority Date: 03/30/2007
• Status: Active Grant

• Current Assignee: Stryker Corporation
• Original Assignee: Orthovita Inc. (Stryker Corporation)
• Inventors: Murphy, James P., Paris, Michael W., Bagga, Charanpreet S., Clineff, Theodore D., Entrekin, Dean A.
• Granted Patent: US 9,539,042 B2
• Time in Patent Office: Days
• US Class Current: 606/94
• CPC Class Codes: A61B 17/8822 characterised by means facilitating expulsion of fluid from the introducer, e.g. a screw pump plunger, hydraulic force transmissions, application of vibrations or a vacuum
• CPC Class Codes: A61B 17/8825 characterised by syringe details A61B17/8822, A61B17/8827 take precedence
• CPC Class Codes: A61B 17/8827 with filtering, degassing, venting or pressure relief means

Abstract

Devices and kits, and methods of their use, for the delivery of viscous compositions are described.

Claims

1. A device for the delivery of a composition, the device comprising:

(a) an elongate chamber having a lumen;

(b) a cap on the proximal end of the chamber having a restricted opening covering the lumen of the chamber;

(c) at least one side port having a lumen, said side port lumen being in fluid communication with the lumen of the elongate chamber;

the axes of the lumens of the chamber and side port forming an angle less than 75 degrees; and

(d) a plunger slidable within the lumen of the elongate chamber from a position proximal to conjunction of the lumens of the side port and elongate chamber to a position distal to said conjunction;

(e) the plunger having an interference member that inhibits removal of the plunger from the elongate chamber; and

(f) the elongate chamber having a locking structure that cooperates with a cooperating locking structure on the plunger when the locking structures are in a locking arrangement with one another.

2. The device of claim 1, wherein the axes of the lumens of the chamber and side port form an angle of about 60 degrees.

3. The device of claim 1, wherein the axes of the lumens of the chamber and side port form an angle of about 45 degrees.

4. The device of claim 1, wherein the cooperation results from rotation of the plunger around its axis.

5. The device of claim 1, wherein the cooperation maintains the distal end of the plunger at the position proximal to the conjunction of the lumens.

6. The device of claim 1, wherein the side port further comprises a flow regulation element.

7. The device of claim 1, wherein the side port is detachable from the chamber.

8. The device of claim 1, wherein the side port further comprises at least one filter element.

9. The device of claim 1, wherein the chamber is comprised of a translucent or a transparent material.

10. The device of claim 1, wherein the chamber further comprises an indicator for assessing the contents of the chamber.

11. The device of claim 1, wherein at least one of the elongate chamber, plunger, and side port are comprised of generally flexible material.

12. The device of claim 1, wherein the chamber and the plunger further comprise handles.

13. The device of claim 1, wherein the viscosity of the composition is between 100 centipoise and 400,000 centipoise.

14. The device of claim 1, wherein the viscosity of the composition is between 150,000 centipoise and 400,000 centipoise.

15. The device of claim 1 comprising two side ports.

16. The device of claim 1, further comprising at least one cannula or catheter

17. The device of claim 16, wherein the cannula or catheter is fixably attached to the elongate chamber.

18. The device of claim 1, wherein the plunger comprises a lumen.

19. The device of claim 18, further comprising a penetrable barrier within the plunger lumen.

20. The device of claim 18, further comprising a plunger insert.

21. A device for the delivery of a composition, the device comprising:

(a) an elongate chamber having a lumen;

(b) a cap on the proximal end of the chamber having a restricted opening covering the lumen of the chamber;

(c) at least one side port having a lumen, said side port lumen being in fluid communication with the lumen of the elongate chamber; and

(d) a plunger slidable within the lumen of the elongate chamber from a position proximal to conjunction of the lumens of the side port and elongate chamber to a position distal to said conjunction; and

(e) the plunger having an interference member that inhibits removal of the plunger from the elongate chamber.

22. The device of claim 21, wherein the elongate chamber further comprises a locking structure that cooperates with a cooperating locking structure on the plunger when the locking structures are in a locking arrangement with one another.

23. The device of claim 21, wherein the axes of the lumens of the chamber and side port form an angle less than 75 degrees.

24. A device for the delivery of a composition, the device comprising:

(a) an elongate chamber having a lumen;

(b) a cap on the proximal end of the chamber having a restricted opening covering the lumen of the chamber;

(c) at least one side port having a lumen, said side port lumen being in fluid communication with the lumen of the elongate chamber;

(d) a plunger slidable within the lumen of the elongate chamber from a position proximal to conjunction of the lumens of the side port and elongate chamber to a position distal to said conjunction; and

(e) the elongate chamber having a locking structure that cooperates with a cooperating locking structure on the plunger when the locking structures are in a locking arrangement with one another.

25. The device of claim 24, wherein the plunger further comprises an interference member that inhibits removal of the plunger from the elongate chamber.

26. The device of claim 24, wherein the axes of the lumens of the chamber and side port form an angle less than 75 degrees.

27. A kit for the delivery of compositions comprising:

a device for the delivery of a composition, the device comprising;

(a) an elongate chamber having a lumen;

(b) a cap on the proximal end of the chamber having a restricted opening covering the lumen of the chamber;

(c) at least one side port having a lumen, said side port lumen being in fluid communication with the lumen of the elongate chamber;

the axes of the lumens of the chamber and side port forming an angle less than 75 degrees; and

(d) a plunger slidable within the lumen of the elongate chamber from a position proximal to conjunction of the lumens of the side port and elongate chamber to a position distal to said conjunction; and

(e) the plunger having an interference member that inhibits removal of the plunger from the elongate chamber; and

a catheter and/or cannula.

28. The kit of claim 27 further wherein the elongate chamber further comprises a locking structure on that cooperates with a cooperating locking structure on the plunger when the locking structures are in a locking arrangement with one another.

29. The kit of claim 27 further comprising at least one flexible extension.

30. The kit of claim 27 further comprising a reamer.

31. The kit of claim 27 further comprising a needle and/or a stylet.

32. A kit for the delivery of compositions comprising;

a device for the delivery of a composition, the device comprising;

(a) an elongate chamber having a lumen;

(b) a cap on the proximal end of the chamber having a restricted opening covering the lumen of the chamber;

(c) at least one side port having a lumen, said side port lumen being in fluid communication with the lumen of the elongate chamber;

the axes of the lumens of the chamber and side port forming an angle less than 75 degrees; and

(d) a plunger slidable within the lumen of the elongate chamber from a position proximal to conjunction of the lumens of the side port and elongate chamber to a position distal to said conjunction; and

(e) the elongate chamber having a locking structure that cooperates with a cooperating locking structure on the plunger when the locking structures are in a locking arrangement with one another; and

a catheter and/or cannula.

33. The kit of claim 32, wherein the plunger further comprises an interference member that inhibits removal of the plunger from the elongate chamber.

34. The kit of claim 32 further comprising at least one flexible extension.

35. The kit of claim 32 further comprising a reamer.

36. The kit of claim 32 further comprising a needle and/or a stylet.