Methods, Systems, and Computer Program Products For Hierarchical Registration Between a Blood Vessel and Tissue Surface Model For a Subject and a Blood Vessel and Tissue Surface Image For the Subject
First Claim
1. A method for hierarchical registration of a blood vessel model to blood vessel image data, the method comprising:
- (a) mapping a vascular model for a subject to a target vascular image for the subject using a global rigid transformation;
(b) hierarchically mapping individual vessel branches in the model using piecewise rigid transformations to form a piecewise-rigid-transformed vascular model; and
(c) hierarchically mapping individual vessel branches in the piecewise-rigid-transformed vascular model to the target image using piecewise deformable transformations to form a piecewise-deformably-transformed vascular model.
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Accused Products
Abstract
Methods, systems, and computer program products for hierarchical registration (102) between a blood vessel and tissue surface model (100) for a subject and a blood vessel and tissue surface image for the subject are disclosed. According to one method, hierarchical registration of a vascular model to a vascular image is provided. According to the method, a cascular model is mapped to a target image using a global rigid transformation to produce a global-rigid-transformed model. Piecewise rigid transformations are applied in a hierarchical manner to each vessel tree in the global-rigid-transformed model to perform a piecewise-rigid-transformed model. Piecewise deformable transformations are applied to branches in the vascular tree in the piecewise-transformed-model to produce a piecewise-deformable-transformed model.
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Citations
21 Claims
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1. A method for hierarchical registration of a blood vessel model to blood vessel image data, the method comprising:
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(a) mapping a vascular model for a subject to a target vascular image for the subject using a global rigid transformation; (b) hierarchically mapping individual vessel branches in the model using piecewise rigid transformations to form a piecewise-rigid-transformed vascular model; and (c) hierarchically mapping individual vessel branches in the piecewise-rigid-transformed vascular model to the target image using piecewise deformable transformations to form a piecewise-deformably-transformed vascular model. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A method for hierarchical registration between a blood vessel and tissue surface model for a subject and a blood vessel and tissue surface image for the subject, the method comprising:
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(a) generating a blood vessel model and a tissue surface model from a source blood vessel and tissue surface image for a subject; (b) performing a plurality of hierarchical registrations between the blood vessel model and the tissue surface model and a target blood vessel and tissue surface image for the subject to produce transformations between locations in between locations in the models and locations in the target image; and (c) determining, based on the transformations in locations, a location of a feature from the source blood vessel and tissue surface image in the transformed blood vessel and tissue surface model. - View Dependent Claims (10, 11, 12, 13, 14)
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15. A system for hierarchical blood vessel and tissue surface model to image registration, the system comprising:
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(a) a blood vessel and tissue surface model generator for receiving a source blood vessel and tissue surface image for a subject and generating a vascular model and a tissue surface model for the subject; and (b) a hierarchical blood vessel and tissue surface model-to-image registration module for receiving as input the vascular model, the tissue surface model, a target blood vessel and tissue surface image, and a feature of interest in the source blood vessel and tissue surface image and for performing hierarchical blood vessel and tissue surface model-to-image registrations to produce a model with a target-image-registered feature of interest. - View Dependent Claims (16, 17, 18, 19)
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20. A computer program product comprising computer-executable instructions embodied in a computer-readable medium for performing steps comprising:
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(a) mapping a vascular model for a subject to a target vascular image for the subject using a global rigid transformation; (b) hierarchically mapping individual vessel branches in the model using piecewise rigid transformations to form a piecewise-rigid-transformed vascular model; and (c) hierarchically mapping individual vessel branches in the piecewise-rigid-transformed vascular model to the target image using piecewise deformable transformations to form a piecewise-deformably-transformed vascular model.
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21. A computer program product comprising computer-executable instructions embodied in a computer-readable medium for performing steps comprising:
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(a) generating a blood vessel model and a tissue surface model from a source blood vessel and tissue surface image for a subject; (b) performing a plurality of hierarchical registrations between the blood vessel model and the tissue surface model and a target blood vessel and tissue surface image for the subject to produce transformations between locations in between locations in the models and locations in the target image; and (c) determining, based on the transformations in locations, a location of a feature from the source blood vessel and tissue surface image in the transformed blood vessel and tissue surface model.
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Specification