Biosensor

• US 20080257728A1
• Filed: 01/31/2008
• Published: 10/23/2008
• Est. Priority Date: 09/12/1997
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Therasense Incorporated (Abbott Laboratories Incorporated)
• Inventors: Mure, Hiroki, Shirakawa, Hiroshi, Gotoh, Masao
• Granted Patent: US 7,901,554 B2
• Time in Patent Office: Days
• US Class Current: 204/403.14
• CPC Class Codes: C12Q 1/005 involving specific analytes or enzymes including groups of enzymes, e.g. oxydases; C12Q1/004 takes precedence
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52
• CPC Class Codes: Y10S 435/817 Enzyme or microbe electrode

Abstract

A biosensor comprises a space part for sucking and housing a sample formed of two upper and lower plates, the two plates being stuck together by an adhesive layer, the space part for sucking and housing the sample being constituted so as to be partially opened in the peripheral part and partially closed by the adhesive layer, and has a working electrode having at least glucose oxidase immobilized thereon and a counter electrode on the same plane of the plate.

Claims

1. A biosensor comprising:

a plurality of electrodes separated by a space of 100-500 μ

m;

at least one layer;

a space for housing a sample and the opening is in communication with the space for housing the sample, wherein the space has a volume that is no more than 1.0 μ

L.

2. The biosensor of claim 1, wherein the space has a volume that is no more than 0.5 μ

L.

3. The biosensor of claim 1, wherein at least one said layer including an end having a tapered part.

4. The biosensor of claim 3, wherein at least one said electrode is a working electrode having a tip part, wherein said working electrode is provided on said tapered part.

5. The biosensor of claim 1, further comprising a counter electrode.

6. The biosensor of claim 1, wherein at one said electrode is constructed of a gold material.

7. The biosensor of claim 1, further comprising an analyte-responsive enzyme.

8. The biosensor of claim 7, wherein the analyte-responsive enzyme comprising of at least one of glucose oxidase and/or glucose dehydrogenase.

9. The biosensor of claim 1, wherein at least one electrode is a working electrode and a counter electrode are provided on a same layer.

10. The biosensor of claim 1, wherein said electrodes include at least one working electrode, one counter electrode and one reference electrode and are provided on a same layer.

11. The biosensor of claim 1, wherein the working electrode and the counter electrode are provided on different layers.

12. The biosensor of claim 3, further comprising a reference electrode and a tip part of the reference electrode is provided on the tapered part.

13. The biosensor of claim 9, further comprising a third layer having at least one adhesive.

14. The biosensor of claim 1, wherein the biosensor is connectable to a device body having a control part including a display part, and the biosensor further comprises a biosensor insertion signal terminal for interconnecting, upon connecting the biosensor to the device body, two input terminals of the device body to start the control part of the device body.

15. The biosensor of claim 1, wherein the biosensor is connectable to a device body having a control part including a display part and the biosensor further comprises a biosensor insertion signal terminal for interconnecting, upon connecting the biosensor to the device body, two input terminals of the device body to start the control part of the device body.

16. The biosensor of claim 3, wherein the tapered part includes an opening for admitting sample.