Method and System for Radiopharmaceutical Kit Preparation
First Claim
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1. A kit preparation system comprising:
- a housing defining a preparation cavity, said housing formed from a radiation-shielding material;
a syringe comprising an elongate hollow needle connected to a hollow syringe barrel supporting a slideable syringe piston therein;
a syringe actuator for extending and retracting said syringe piston;
a vial holder for holding the pierceable septum for a vial in registry with the needle tip of said syringe;
a translational mechanism for extending the needle tip through the septum of the vial.
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Abstract
An automated system for remotely drawing and dispensing eluate in preparing kits of radioactive pharmaceuticals. The system includes cradles for holding shielded vials containing eluate or the final kit from cold kit vials. The present invention also provides methods and apparati directed to the withdrawal and dispensing of eluate while reducing waste and exposure to operators.
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Citations
47 Claims
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1. A kit preparation system comprising:
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a housing defining a preparation cavity, said housing formed from a radiation-shielding material; a syringe comprising an elongate hollow needle connected to a hollow syringe barrel supporting a slideable syringe piston therein; a syringe actuator for extending and retracting said syringe piston; a vial holder for holding the pierceable septum for a vial in registry with the needle tip of said syringe; a translational mechanism for extending the needle tip through the septum of the vial.
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2-18. -18. (canceled)
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19. A cradle for holding a vial containing contents to be withdrawn, said cradle comprising:
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a cradle base; at least one upstanding wall supported on said cradle base; a vial retention mechanism defining a vial cavity for accepting a vial, said retention mechanism releasably engaging a vial in said vial cavity; and a crownpiece supported by said at least one upstanding wall to extend over said vial cavity, said crownpiece defining a first aperture therethrough in overlying registry with said vial cavity - View Dependent Claims (20, 23, 24, 25, 26, 27, 28, 29, 30, 32)
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21. (canceled)
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22. (canceled)
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31. (canceled)
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33. A method of withdrawing the contents from a vial with an automated fluid transfer device, wherein said vial defines an interior chamber and includes a planar base, an upstanding cylindrical wall and a pierceable septum about said interior chamber, and wherein said transfer device includes an elongate syringe supporting an elongate needle wherein said syringe and vial are linearly moveable with respect to each other so as to allow said needle to pierce a septum of said vial, comprising the step of:
placing the vial into a vial holder which holds the vial in a slanted geometry with respect to the needle so that the needle may reach the lowest portion of said vial chamber as defined between the planar base and cylindrical wall. - View Dependent Claims (34, 35, 40)
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36. (canceled)
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37. (canceled)
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41. (canceled)
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42. A method of dispensing the contents of a syringe in an automated dispense system into a kit vial, wherein the kit vial defines an interior chamber and includes a planar base, an upstanding cylindrical wall and a pierceable septum about the interior chamber, and wherein the transfer device includes an elongate syringe supporting an elongate needle wherein the syringe and vial are linearly moveable with respect to each other so as to allow the needle to pierce a septum of the vial, comprising the steps of:
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Placing the vial, within its shield, into a vial holder; and Inserting the tip of an elongate overflow needle through the vial holder into the vial chamber. - View Dependent Claims (43)
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44. (canceled)
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47. (canceled)
Specification