Automated Therapy System and Method

• US 20080262418A1
• Filed: 04/04/2008
• Published: 10/23/2008
• Est. Priority Date: 04/05/2007
• Status: Active Grant

• Current Assignee: Theranova, Llc
• Original Assignee: Velomedix, Inc.
• Inventors: Hermanson, Christopher, Burnett, Daniel Rogers, Rajguru, Amit, Hall, Gregory
• Granted Patent: US 8,100,880 B2
• Time in Patent Office: Days
• US Class Current: 604/66
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/02055 Simultaneously evaluating both cardiovascular condition and temperature
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/068 using impedance sensors
• CPC Class Codes: A61B 5/14507 specially adapted for measuring characteristics of body fluids other than blood devices for taking samples of body liquids A61B10/0045
• CPC Class Codes: A61B 5/207 Sensing devices adapted to collect urine
• CPC Class Codes: A61B 5/208 adapted to determine urine quantity, e.g. flow, volume
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61F 2007/0022 Abdomen
• CPC Class Codes: A61F 2007/0063 for cooling
• CPC Class Codes: A61F 2007/0093 programmed
• CPC Class Codes: A61F 2007/126 for invasive application, e.g. for introducing into blood vessels
• CPC Class Codes: A61F 7/0085 Devices for generating hot or cold treatment fluids
• CPC Class Codes: A61F 7/12 Devices for heating or cooling internal body cavities
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 2025/0166 Sensors, electrodes or the like for guiding the catheter to a target zone, e.g. image guided or magnetically guided
• CPC Class Codes: A61M 2205/3303 Using a biosensor
• CPC Class Codes: A61M 2230/04 Heartbeat characteristics, e.g. ECG, blood pressure modulation
• CPC Class Codes: A61M 2230/10 Electroencephalographic signals
• CPC Class Codes: A61M 2230/202 partial carbon oxide pressure, e.g. partial dioxide pressure (P-CO2)
• CPC Class Codes: A61M 2230/205 : partial oxygen pressure (P-O2)
• CPC Class Codes: A61M 2230/208 : pH-value
• CPC Class Codes: A61M 2230/65 : Impedance, e.g. conductivity, capacity
• CPC Class Codes: A61M 5/142 : Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/1723 : using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

An automated therapy system having an infusion catheter; a sensor adapted to sense a patient parameter; and a controller communicating with the sensor and programmed to control flow output from the infusion catheter into a patient based on the patient parameter without removing fluid from the patient. The invention also includes a method of controlling infusion of a fluid to a patient. The method includes the following steps: monitoring a patient parameter with a sensor to generate a sensor signal; providing the sensor signal to a controller; and adjusting fluid flow to the patient based on the sensor signal without removing fluid from the patient.

Claims

1. An automated therapy system comprising:

an infusion catheter;

a sensor adapted to sense a patient parameter; and

a controller communicating with the sensor and programmed to control flow output from the infusion catheter into a patient based on the patient parameter without removing fluid from the patient.

2. The system of claim 1 wherein the sensor is incorporated into the catheter.

3. The system of claim 1 wherein the sensor is separate from the catheter.

4. The system of claim 1 wherein the sensor comprises an ECG sensor.

5. The system of claim 1 wherein the sensor comprises an EEG sensor.

6. The system of claim 1 wherein the sensor comprises a pulse oximetry sensor.

7. The system of claim 1 wherein the sensor comprises a blood pressure sensor.

8. The system of claim 1 wherein the sensor comprises a cardiac output sensor.

9. The system of claim 8 wherein the sensor comprises a thermodilution cardiac output sensor.

10. The system of claim 1 wherein the sensor comprises a cardiac stroke volume sensor.

11. The system of claim 1 wherein the sensor comprises a heart rate sensor.

12. The system of claim 1 wherein the sensor comprises a blood flow sensor.

13. The system of claim 1 wherein the sensor comprises a pH sensor.

14. The system of claim 1 wherein the sensor comprises a blood pO₂ sensor.

15. The system of claim 1 wherein the sensor comprises a solute sensor.

16. The system of claim 1 wherein the catheter comprises a peripheral venous catheter.

17. The system of claim 1 wherein the catheter comprises a central venous catheter.

18. The system of claim 1 wherein the catheter comprises an arterial catheter.

19. The system of claim 1 wherein the catheter comprises a peritoneal catheter.

20. The system of claim 19 wherein the sensor comprises an intraperitoneal pressure sensor.

21. A method of controlling infusion of a fluid to a patient comprising:

monitoring a patient parameter with a sensor to generate a sensor signal;

providing the sensor signal to a controller; and

adjusting fluid flow to the patient based on the sensor signal without removing fluid from the patient.

22. The method of claim 21 further comprising monitoring cardiac output with the sensor.

23. The method of claim 22 further comprising adjusting fluid flow to the patient based on cardiac output monitored by the sensor.

24. The method of claim 21 wherein the patient parameter comprises an electrocardiogram.

25. The method of claim 21 wherein the patient parameter comprises an electroencephalogram.

26. The method of claim 21 wherein the patient parameter comprises blood oxygen saturation.

27. The method of claim 21 wherein the patient parameter comprises blood pressure.

28. The method of claim 21 wherein the patient parameter comprises cardiac output.

29. The method of claim 21 wherein the patient parameter comprises cardiac stroke volume.

30. The method of claim 21 wherein the patient parameter comprises heart rate.

31. The method of claim 21 wherein the patient parameter comprises blood flow.

32. The method of claim 21 wherein the patient parameter comprises total circulating blood volume.

33. The method of claim 21 wherein the patient parameter comprises whole body oxygen consumption.

34. The method of claim 21 wherein the patient parameter comprises pH.

35. The method of claim 21 wherein the patient parameter comprises blood pO₂.

36. The method of claim 21 wherein the patient parameter comprises osmolarity.

37. The method of claim 21 wherein the patient parameter comprises peritoneal cavity compliance.

38. The method of claim 21 wherein the patient parameter comprises intrathoracic pressure.

39. The method of claim 21 wherein the patient parameter comprises bladder pressure.

40. The method of claim 21 wherein the patient parameter comprises rectal pressure.

41. The method of claim 21 wherein the adjusting step comprises adjusting fluid flow to achieve or maintain patient euvolumia.

42. The method of claim 21 wherein the adjusting step comprises adjusting flow of a therapeutic agent to the patient.

43. The method of claim 42 wherein the therapeutic agent comprises a chilled medium.

44. The method of claim 21 wherein the adjusting step comprises adjusting fluid flow to the patient through a peripheral venous catheter.

45. The method of claim 21 wherein the adjusting step comprises adjusting fluid flow to the patient through a central venous catheter.

46. The method of claim 21 wherein the adjusting step comprises adjusting fluid flow to the patient through an arterial catheter.

47. The method of claim 21 wherein the adjusting step comprises adjusting fluid flow to the patient'"'"'s peritoneal cavity.

48. A method of treating hypotension in a patient, the method comprising:

monitoring a patient parameter with a sensor to generate a sensor signal;

providing the sensor signal to a controller; and

adjusting fluid flow to the patient based on the sensor signal without removing fluid from the patient.

49. The method of claim 48 wherein the patient parameter is blood pressure.

50. The method of claim 48 wherein the patient parameter is cardiac output.

51. A method of treating sepsis in a patient, the method comprising:

monitoring a patient parameter with a sensor to generate a sensor signal;

providing the sensor signal to a controller; and

adjusting fluid flow to the patient based on the sensor signal without removing fluid from the patient.

52. The method of claim 51 wherein the patient parameter is blood pressure.

53. The method of claim 51 wherein the patient parameter is cardiac output.

54. A method of inducing and reversing therapeutic hypothermia in a patient, the method comprising:

monitoring intracranial pressure to generate a sensor signal;

providing the sensor signal to a controller; and

adjusting rate of hypothermia induction or rewarming based on intracranial pressure.