SAMPLE STORAGE FOR LIFE SCIENCE
First Claim
Patent Images
1. A liquid-storable biological sample, comprising:
- (a) a biological sample;
(b) a liquid matrix that comprises a matrix material dissolved or dissociated in a biocompatible solvent; and
(c) at least one stabilizer,wherein (a), (b) and (c) are in fluid contact with one another for at least one day without refrigeration, andwherein substantially all biological activity of the liquid-storable biological sample is recoverable following storage without refrigeration for a time period of at least one day.
2 Assignments
0 Petitions
Accused Products
Abstract
Compositions and methods are disclosed for liquid storage of biological samples with recovery of substantially all biological activity and without refrigeration. Also disclosed are compositions and methods for automated storing, tracking retrieving and analyzing of such liquid-storable biological samples, including nucleic acids and proteins (including enzymes). RFID-tagged liquid-storable biological sample storage devices featuring liquid matrices are disclosed, as also are computer-implemented systems and methods for managing sample data.
54 Citations
70 Claims
-
1. A liquid-storable biological sample, comprising:
-
(a) a biological sample; (b) a liquid matrix that comprises a matrix material dissolved or dissociated in a biocompatible solvent; and (c) at least one stabilizer, wherein (a), (b) and (c) are in fluid contact with one another for at least one day without refrigeration, and wherein substantially all biological activity of the liquid-storable biological sample is recoverable following storage without refrigeration for a time period of at least one day. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 19, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 69)
-
-
18. (canceled)
-
20. A liquid-storable biological sample, comprising:
-
(a) a biological sample; (b) a liquid matrix that comprises polyvinyl alcohol dissolved in a biocompatible solvent; and (c) at least one stabilizer which comprises validamycin, wherein (a), (b) and (c) are in fluid contact with one another for at least one day without refrigeration, and wherein substantially all biological activity of the liquid-storable biological sample is recoverable following storage without refrigeration for a time period of at least one day.
-
-
36-53. -53. (canceled)
-
54. A liquid-storable biological sample, comprising:
-
(a) a biological sample; (b) a liquid matrix that comprises a matrix material dissolved or dissociated in a biocompatible solvent; (c) at least one stabilizer; and (d) an activity buffer, wherein (a), (b), (c) and (d) are in fluid contact with one another for at least one day without refrigeration, and wherein substantially all biological activity of the liquid-storable biological sample is recoverable following storage without refrigeration for a time period of at least one day. - View Dependent Claims (55)
-
-
56-68. -68. (canceled)
-
70-72. -72. (canceled)
Specification