Biosensor and method of manufacturing biosensor

• US 20080274016A1
• Filed: 07/01/2008
• Published: 11/06/2008
• Est. Priority Date: 09/01/2003
• Status: Active Grant

• Current Assignee: Seiko Epson Corporation (Seiko Group)
• Original Assignee: Seiko Epson Corporation (Seiko Group)
• Inventors: Kondo, Takayuki, Fukushima, Hitoshi
• Granted Patent: US 7,998,413 B2
• Time in Patent Office: Days
• US Class Current: 422/82.05
• CPC Class Codes: G01N 21/553 and using surface plasmons fluorescence excitation G01N21/648; enhanced Raman G01N21/658
• CPC Class Codes: G01N 21/6428 Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" in vivo A61B5/00; immunoassay G01N33/53
• CPC Class Codes: G01N 21/6452 Individual samples arranged in a regular 2D-array, e.g. multiwell plates
• CPC Class Codes: G01N 21/6454 using an integrated detector array

Abstract

Aspects of the invention can be an inexpensive biosensor capable of measuring a number of samples in a short time, and suitable for only one-time use (expendable). The biosensor according to the invention can include a light transmissive substrate, a probe fixing region provided on one face of the light transmissive substrate, a light emitting element provided on the other face of the substrate that irradiates the probe fixing region from the back side thereof, and a light receiving element provided on the other face of the substrate that detects the light intensity of the reflected light from the back side of the probe fixing region. Thereby, a biosensor formed in one substrate can be obtained.

Claims

1. A biosensor, comprising:

a light transmissive substrate;

a plurality of probe fixing regions provided on a first face of the light transmissive substrate;

a light shielding region formed in the light transmissive substrate that shields light between the probe fixing regions; and

a light emitting element that irradiates the probe fixing region from a light transmissive substrate side, and a light receiving element that detects light intensity of the reflected light from the light transmissive substrate side of the probe fixing region, the light emitting element and the light receiving element being provided in each probe fixing region on a second face of the light transmissive substrate.

2. The biosensor according to claim 1, each of the probe fixing regions in the light transmissive substrate being set on a microlens or a microprism formed in the light transmissive substrate.