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TREATMENT PROTOCOL GENERATION FOR DISEASES RELATED TO ANGIOGENESIS

  • US 20080275684A1
  • Filed: 06/03/2008
  • Published: 11/06/2008
  • Est. Priority Date: 10/25/2001
  • Status: Abandoned Application
First Claim
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1. A computer-implemented method for determining an optimal treatment protocol for a disease related to angiogenesis, comprising:

  • creating an angiogenesis model including pro-angiogenesis and anti-angiogenesis factors;

    incorporating effects of vasculature maturation and mature vessels destabilization;

    selecting pro-angiogenesis and anti-angiogenesis factors, which can influence changes in state of a tissue;

    incorporating effects of drugs in the pro-angiogenesis and anti-angiogenesis factors;

    generating a plurality of treatment protocols in a protocol space; and

    selecting a best treatment protocol based on a pre-determined criteria.

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