Photopolymerizable Silicone Materials Forming Semipermeable Membranes for Sensor Applications
First Claim
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1. A method comprising:
- (1) applying a photopatternable silicone composition to a surface in a sensing device to form a film,(b 2) photopatterning the film by a process comprising exposing the film to radiation through a photomask without using a photoresist to produce an exposed film;
(3removing regions of the non-exposed film with a developing solvent to form a patterned film;
optionally (4) heating the patterned film.
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Abstract
A method for preparing sensing devices (biosensors) includes the steps of: (1) applying a photopatternable silicone composition to a surface in a sensing device to form a film, (2) photopatterning the film by a process comprising exposing the film to radiation through a photomask without the use of a photoresist to produce an exposed film; (3) removing regions of the non-exposed film with a developing solvent to form a patterned film, which forms a permselective layer or an analyte attenuation layer covering preselected areas of the sensing device.
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17 Claims
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1. A method comprising:
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(1) applying a photopatternable silicone composition to a surface in a sensing device to form a film, (b 2) photopatterning the film by a process comprising exposing the film to radiation through a photomask without using a photoresist to produce an exposed film; (3removing regions of the non-exposed film with a developing solvent to form a patterned film; optionally (4) heating the patterned film. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A device comprising:
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(i) a substrate, (ii) a base sensor mounted to the substrate, optionally (iii) an electrolyte layer covering the base sensor and at least a portion of the silicon substrate, (iv) a permselective layer covering at least a portion of the base sensor, optionally (v) a biolayer covering at least a portion of the permselective layer, optionally (vi) an analyte attenuation layer covering at least a portion of the biolayer, optionally (vii) a coupling means covering at least a portion of the permselective layer, where the coupling means attach (viii) a ligand receptor or an immunreactive species as an outermost layer of the device; where the permselective layer is a cured product of a photopatternable silicone composition selected from the group consisting of a photopatternable silicone resin composition and a photopatternable hydrosilylation curable silicone composition. - View Dependent Claims (16, 17)
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14. A device comprising:
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(i) a substrate, (ii) a base sensor mounted to the substrate, optionally (iii) an electrolyte layer covering the base sensor and at least a portion of the silicon substrate, (iv) a permselective layer covering at least a portion of the base sensor, (v) a biolayer covering at least a portion of the permselective layer, and (vi) an analyte attenuation layer covering at least a portion of the biolayer; where the analyte attenuation layer is a cured product of a photopatternable silicone composition selected from the group consisting of a photopatternable silicone resin composition and a photopatternable hydrosilylation curable silicone composition. - View Dependent Claims (15)
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Specification