Spiro compounds for treatment of inflammatory disorders
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Accused Products
Abstract
Provided are compounds, pharmaceutical compositions and methods of treatment or prophylaxis of an inflammatory condition, in particular asthma. The compounds are of the general Formula I, or a pharmaceutically acceptable salt, ester, prodrug or derivative thereof:
wherein Y, Z and R1-R12 are defined herein.
13 Citations
39 Claims
- 1. A compound of Formula IV:
- 12. A pharmaceutical composition of Formula I
- 27. A method of treatment or prophylaxis of an inflammatory condition comprising administering a compound of Formula I, optionally in a pharmaceutically acceptable carrier, to a host at risk of, or suffering from, an inflammatory condition
Specification