Elevated coupling liquid temperature during HIFU treatment method and hardware
First Claim
1. A medical procedure comprising:
- providing a high-intensity focused ultrasound instrument having an applicator surface, a liquid-containing bolus acting as a heat sink, and a source of ultrasonic vibrations, said applicator surface being a surface of a flexible wall of said bolus, said source of ultrasonic vibrations being in operative contact with said bolus;
placing said applicator surface in contact with an organ surface of a patient;
energizing said source to produce ultrasonic vibrations focused at a predetermined focal region inside said organ; and
controlling a temperature of liquid in said bolus while said applicator surface is in contact with said organ surface to control temperature elevation in tissues of said organ between said focal region and said organ surface to necrose the tissues to within a desired distance from said organ surface.
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Accused Products
Abstract
A medical procedure utilizes a high-intensity focused ultrasound instrument having an applicator surface, a liquid-containing bolus or expandable chamber acting as a heat sink, and a source of ultrasonic vibrations, the applicator surface being a surface of a flexible wall of the bolus, the source of ultrasonic vibrations being in operative contact with the bolus. The applicator surface is placed in contact with an organ surface of a patient, the source is energized to produce ultrasonic vibrations focused at a predetermined focal region inside the organ, and a temperature of liquid in the bolus is controlled while the applicator surface is in contact with the organ surface to control temperature elevation in tissues of the organ between the focal region and the organ surface to necrose the tissues to within a desired distance from the organ surface.
365 Citations
20 Claims
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1. A medical procedure comprising:
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providing a high-intensity focused ultrasound instrument having an applicator surface, a liquid-containing bolus acting as a heat sink, and a source of ultrasonic vibrations, said applicator surface being a surface of a flexible wall of said bolus, said source of ultrasonic vibrations being in operative contact with said bolus; placing said applicator surface in contact with an organ surface of a patient; energizing said source to produce ultrasonic vibrations focused at a predetermined focal region inside said organ; and controlling a temperature of liquid in said bolus while said applicator surface is in contact with said organ surface to control temperature elevation in tissues of said organ between said focal region and said organ surface to necrose the tissues to within a desired distance from said organ surface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A medical treatment apparatus comprising:
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a high-intensity focused ultrasound instrument having an applicator surface, a bolus acting as a heat sink, and a source of ultrasonic vibrations, said applicator surface being in thermal and operative contact with said bolus, said source of ultrasonic vibrations being in operative contact with said bolus; and means for controlling a temperature of liquid in said bolus while said applicator surface is in contact with said organ surface to control temperature elevation in tissues of said organ between said focal region and said organ surface to necrose the tissues to within a desired distance from said organ surface. - View Dependent Claims (16, 17, 18, 19, 20)
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Specification