Guidewire with adjustable stiffness

• US 20080281228A1
• Filed: 04/11/2008
• Published: 11/13/2008
• Est. Priority Date: 04/23/2007
• Status: Abandoned Application

• Current Assignee: CardioGuidance Biomedical, LLC
• Original Assignee: CardioGuidance Biomedical, LLC
• Inventors: Hinchliffe, Peter W.J., Parodi, Juan Carlos, Mooney, Ivan, Lupton, Henry, Donohue, Colin
• Application Number:
  US12/082,506
• Publication Number:
  US 20080281228A1
• Time in Patent Office: Days
• US Class Current: 600/585
• CPC Class Codes: A61M 2025/0006 which can be secured against axial movement, e.g. by using a locking cuff
• CPC Class Codes: A61M 2025/0042 Microcatheters, cannula or the like having outside diameters around 1 mm or less
• CPC Class Codes: A61M 2025/09075 having a core without a coil possibly combined with a sheath
• CPC Class Codes: A61M 2025/09083 having a coil around a core
• CPC Class Codes: A61M 2025/09091 where a sheath surrounds the coil at the distal part
• CPC Class Codes: A61M 2025/09116 Design of handles or shafts or gripping surfaces thereof for manipulating guide wires
• CPC Class Codes: A61M 2025/09133 having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque
• CPC Class Codes: A61M 2025/0915 having features for changing the stiffness
• CPC Class Codes: A61M 2025/09175 having specific characteristics at the distal tip
• CPC Class Codes: A61M 25/09 Guide wires
• CPC Class Codes: A61M 25/09025 with sliding mandrils

Abstract

A method of adjusting the stiffness and size of a guidewire without full withdrawal of the guidewire from a patient'"'"'s vascular system comprising providing a guidewire system comprising an inner member having a first outer diameter and a first stiffness, an outer member having a third larger diameter and a third stiffness, and a stiffener positioned between the inner and outer members and having a second outer diameter larger than the first diameter and smaller than the third diameter. The method includes selectively changing the relative positions of the members to alter the pushability and stiffness of the guidewire system.

Claims

1. A method of adjusting the stiffness and size of a guidewire without full withdrawal of the guidewire from a patient'"'"'s vascular system, the method comprising:

a) providing a guidewire system comprising an inner member having a first outer diameter and a first stiffness, an outer member having a third larger diameter and a third stiffness, and a stiffener positioned between the inner and outer members and having a second outer diameter larger than the first diameter and smaller than the third diameter;

b) advancing the guidewire system into the vascular system with the outer member and stiffener in the retracted position to expose a substantial length of the inner member to expose a smaller member diameter;

c) after advancement of the guidewire system through the vascular system in step (b), selectively changing the relative position of the outer member and inner member to provide a stiffer member to increase the pushability of the guidewire system if desired; and

d) thereafter, if desired, selectively advancing the stiffener to further increase the stiffness of the guidewire system to a second stiffness greater than the third stiffness.

2. The method of claim 1, further comprising the step of attaching a distal end of an extension wire to the proximal end of the inner member.

3. The method of claim 1, further comprising the step of detaching a proximal handle of the inner member to enable removal of the outer member and stiffener to leave the inner member in position for over the wire catheter insertion.

4. The method of claim 1, further comprising the step of interlocking the stiffener and the outer member to fix the position of the stiffener and the outer member.

5. The method of claim 1, further comprising the step of leaving the outer member in an advanced position to present a larger diameter rail for over the wire insertion of a device.

6. The method of claim 1, further comprising the step of interlocking the stiffener and the inner member to fix the position of the inner member.

7. A method of adjusting the stiffness of a guidewire extending into the vascular system of a patient, the method comprising:

a) providing a guidewire having an inner member having a first outer diameter and a first stiffness, an outer member having a third larger diameter and a third stiffness, and a stiffener positioned between the inner and outer members and having a second outer diameter larger than the first diameter and smaller than the third diameter;

b) advancing the guidewire into the vascular system from a remote site with the outer member and stiffener in the retracted position to expose a substantial length of the inner member;

c) when encountering a tortuous vessel portion wherein the inner member lacks the requisite pushability, changing the relative positions of the inner member and the outer member without removing the inner member from the patient so the outer member covers a distal portion of the inner member to create a stiffer guidewire; and

d) when encountering a restricted passage in a portion of the vessel, changing the relative positions of the inner member and outer member to expose at least a portion of the covered distal portion of the inner member.

8. The method of claim 7, wherein the exposed length and exposed portion of the inner member in step (b) and step (d) is the substantially the same.

9. The method of claim 7, further comprising the step of advancing the stiffener within the outer member to increase the stiffness of the guidewire to a second stiffness greater than the third stiffness when encountering a tortuous passage of the vessel in which the outer member lacks the requisite pushability.

10. The method of claim 9, further comprising the step of detaching a proximal handle of the inner member to enable removal of the outer member and stiffener members to leave the inner member in position for over the wire catheter insertion.

11. The method of claim 7, further comprising the step of interlocking the stiffener and the outer member to fix the position of the stiffener and the outer member.

12. The method of claim 7, further comprising the step of interlocking the stiffener and the inner member to fix the position of the inner member.

13. A method of adjusting the stiffness of a guidewire extending into the vascular system of a patient, the method comprising:

a) providing a guidewire having an inner member having a first outer diameter and a first stiffness, an outer member having a third larger diameter and a third stiffness, and a stiffener positioned between the inner and outer members and having a second outer diameter larger than the first diameter and smaller than the third diameter;

b) advancing the guidewire into the vascular system from a remote site with the outer member in the extended position and the stiffener and inner member in an unexposed retracted position;

c) when encountering a vessel portion wherein the outer member is too large for advancement or lacks the requisite flexibility, changing the relative positions of the inner member and the outer member without removing the outer member from the patient so a portion of the inner member is exposed; and

d) when encountering a tortuous vessel portion wherein the inner member lacks the requisite pushability, changing the relative positions of the inner member and outer member to retract the inner member to leave the outer member as the distalmost region of the guidewire.

14. The method of claim 13, further comprising the step of detaching a proximal handle of the inner member to enable removal of the outer member and stiffener to leave the inner member in position for over the wire catheter insertion.

15. The method of claim 13, further comprising the step of interlocking the stiffener and the outer member to fix the position of the stiffener and the outer member.

16. The method of claim 13, further comprising the step of interlocking the stiffener and the inner member to fix the position of the inner member.

17. The method of claim 13, further comprising the step of advancing the stiffener within the outer member to increase the stiffness of the guidewire system to a second stiffness greater than the third stiffness when encountering a tortuous passage of the vessel in which the outer member lacks the requisite pushability.