Bioabsorbable Self-Expanding Endolumenal Devices

• US 20080281393A1
• Filed: 07/28/2008
• Published: 11/13/2008
• Est. Priority Date: 08/02/2004
• Status: Active Grant

• Current Assignee: W. L. Gore & Associates (W.L. Gore & Associates)
• Original Assignee: W. L. Gore & Associates (W.L. Gore & Associates)
• Inventors: Cleek, Robert L., Cully, Edward H., White, Charles F., Flynn, Charles, Hayes, Byron K., Armstrong, Joseph R., Vonesh, Michael J., Peterson, Ryan V., Begovac, Paul C.
• Granted Patent: US 9,005,269 B2
• Time in Patent Office: Days
• US Class Current: 623/1.2
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61F 2/01 Filters implantable into blood vessels
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2002/30062 (bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
• CPC Class Codes: A61F 2002/91508 the meander having a difference in amplitude along the band
• CPC Class Codes: A61F 2002/91525 within the whole structure different bands showing different meander characteristics, e.g. frequency or amplitude
• CPC Class Codes: A61F 2002/91533 characterised by the phase between adjacent bands
• CPC Class Codes: A61F 2002/9155 Adjacent bands being connected to each other
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2210/0076 multilayered, e.g. laminated structures
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/008 : paraboloidal
• CPC Class Codes: A61F 2250/003 : differing in adsorbability or resorbability, i.e. in adsorption or resorption time
• CPC Class Codes: A61L 31/06 : obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds A61L31/041 takes precedence
• CPC Class Codes: A61L 31/148 : Materials at least partially resorbable by the body
• CPC Class Codes: C08L 67/04 : Polyesters derived from hydroxycarboxylic acids, e.g. lactones C08L67/06 takes precedence

Abstract

The present invention is directed to bioabsorbable self-expanding medical devices for use inside or outside body conduits that self-expand at, or below, normal human body temperature without requisite for a polymeric thermal transition.

Claims

1. A self-expanding bioabsorbable support for a body conduit comprising:

a substantially tubular framework delimiting a multiplicity of fenestrations;

wherein said framework is continuous, non-filamentous, non-braided, and non-interlaced;

wherein said framework is made of a non-blended hydrolysable co-polymeric material;

wherein said framework expands radially from a compressed configuration to an uncompressed configuration below normal human body temperature without requisite for an externally applied force and without requisite for a thermal transition of said polymeric material; and

wherein said framework does not change axial length following compaction or radial expansion of said framework.

2. The support of claim 1 wherein said fenestrations are laser-cut.

3. The support of claim 1 wherein said non-blended hydrolyzable co-polymeric material is a tri-block co-polymer of poly(glycolide) and poly(trimethylenecarbonate).

4. The support of claim 1 further comprising an agent combined with said polymeric material.

5. The support of claim 4 wherein said agent is a bioactive agent.

6. The support of claim 4 wherein said agent is a non-bioactive agent.

7. The support of claim 6 wherein said non-bioactive agent is radiopaque.

8. The support of claim 5 wherein said bioactive agent is dexamethasone.