Pharma-Informatics System
5 Assignments
0 Petitions
Accused Products
Abstract
Compositions, systems and methods that allow for the detection of the actual physical delivery of a pharmaceutical agent to a body are provided. Embodiments of the compositions include an identifier and an active agent. The invention finds use in a variety of different applications, including but not limited to, monitoring of therapeutic regimen compliance, tracking the history of pharmaceutical agents, etc.
424 Citations
97 Claims
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1. (canceled)
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2. A composition comprising:
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an active agent; an identifier that emits a signal when interrogated; and a pharmaceutically acceptable carrier; wherein said composition is disrupted upon administration to a subject. - View Dependent Claims (3, 4, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 27, 28, 29, 33, 37, 38, 40, 43, 44, 60, 61, 62, 63, 64, 65)
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5-6. -6. (canceled)
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25. (canceled)
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26. (canceled)
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30. (canceled)
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31. (canceled)
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32. (canceled)
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34. (canceled)
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35. (canceled)
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36. (canceled)
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39. (canceled)
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41-42. -42. (canceled)
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45-59. -59. (canceled)
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66. (canceled)
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67. A method comprising:
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(a) interrogating a composition comprising; an active agent; an identifier that emits a signal when interrogated; and a pharmaceutically acceptable carrier; wherein such composition is disrupted upon administration to a subject, to obtain data for said composition; and (b) determining historical information for said composition from said data. - View Dependent Claims (68)
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69-74. -74. (canceled)
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75. A method of manufacturing an active agent composition, said method comprising:
combining an identifier that is activated upon contact with a target physiological location to emit a signal with an active agent and a pharmaceutically acceptable carrier in a manner sufficient to produce said composition. - View Dependent Claims (76, 77, 78)
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79-82. -82. (canceled)
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83. A battery smaller than 10 mm3 comprising two materials with dissimilar electrochemical activities that is activated upon contact with a physiological fluid.
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84-89. -89. (canceled)
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90. A method of producing a battery comprising:
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providing a planar semiconductor support material having a first and second surface; producing a first material having a first electrochemical activity on first surface of said support; and producing a second material having a second electrochemical activity on a second surface of said support, wherein said first and second electrochemical activities are different; to produce said battery.
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91-94. -94. (canceled)
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95. An identifier comprising:
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(a) a power source and (b) a signal generating element that emits a signal upon contact with a target body site.
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96. An identifier comprising:
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(a) a power source that transduces broadcast power and (b) a signal generating element that modulates the amount of transduced power upon contact with a target body site.
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97-98. -98. (canceled)
Specification