Blood Pressure Monitoring Device and Methods for Making and for Using Such a Device

• US 20080287813A1
• Filed: 03/03/2004
• Published: 11/20/2008
• Est. Priority Date: 03/30/2004
• Status: Abandoned Application

• Current Assignee: ETH Zurich, Universitat Of Zurich
• Original Assignee: ETH Zurich, Universität Zürich
• Inventors: Zund, Gregor, Brand, Oliver, Kirstein, Kay-Uwe, Sedivy, Jan, Grunenfelder, Jurg, Salo, Tomi
• Application Number:
  US10/599,187
• Publication Number:
  US 20080287813A1
• Time in Patent Office: Days
• US Class Current: 600/488
• CPC Class Codes: A61B 2562/0247 Pressure sensors
• CPC Class Codes: A61B 2562/046 in a matrix array
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/02125 of pulse wave propagation time
• CPC Class Codes: A61B 5/489 Blood vessels

Abstract

Disclosed are a system and a method for noninvasively and continuously monitoring blood pressure. Also disclosed is a method for making such a device. The system includes a semiconductor chip comprising a transducer array of individual pressure or force sensors and associated circuitry providing control signals to and/or processing signals from these sensors, all of the above integrated in the chip. Also disclosed is a specific sensor structure provided on said chip. The invention further encompasses a system for measuring and/or tracking the blood pressure waveform and for combining the latter with related blood values like the heartbeat, derived from the above or other measuring devices.

Claims

1. A transducer for continuously and noninvasively measuring blood pressure in a blood vessel, having integrated into a single semiconductor chip:

an array of transducer or sensor elements,

means for reading out data from said sensor elements, and

means for converting said data into a transmittable form.

2. The blood pressure transducer according to claim 1, further including interface means for transmitting said data from said chip to an external computer.

3. The blood pressure transducer according to claim 1, wherein the semiconductor chip is a CMOS chip.

4. The blood pressure transducer according to claim 1, wherein each sensor element comprises a fluid-filled capacitive sensor having a flexible electrode or membrane and a rigid electrode and a fluid gap connected to an opening.

5. The blood pressure transducer according to claim 1, wherein each sensor element comprises a resistive sensor having strain sensitive resistors on a flexible structure of cross-linked beams a flexible protective membrane and a fluid gap connected to openings.

6. The blood pressure transducer according to claim 1, wherein the sensor elements are arranged in a square array.

7. The blood pressure transducer according to claim 6, wherein the array comprises at least 2×

2 sensor elements, preferably 4×

4 sensor elements.

8. The blood pressure transducer according to claim 4, wherein the array comprises 2×

2 sensor elements arranged with adjacent openings located in the center of said array.

9. The blood pressure transducer according to claim 7, wherein the array of sensor elements is placed close to one end of the semiconductor chip.

10. The blood pressure transducer according to claim 1, wherein the semiconductor chip is part of a sensing device which further includes a power source.

11. The blood pressure transducer according to claim 2, wherein the interface means for transmitting the data from said chip to an external computer is a wireless transmission means.

15. A method for using a transducer according to claim 1 for continuously and noninvasively measuring and monitoring blood pressure in a blood vessel, the method comprising the steps of:

extracting directional information from said continuous blood pressure measurement data to locate arteries and/or veins, and/or

extracting characteristic signal features from said continuous blood pressure measurement data to differentiate between arteries and veins.

16. A method for using a transducer according to 11claim 1 for continuously and noninvasively measuring and monitoring blood pressure in a blood vessel, the method comprising the steps of:

producing a map pattern of said continuous blood pressure measurement data to identify abrupt features, in particular blockages due to calcification inside arteries and veins.

12. A system for continuously and noninvasively measuring and monitoring blood pressure in a blood vessel, comprising a sensing device including a single semiconductor chip having integrated:

an array of sensor elements overlying said blood vessel,

means for reading out data from said sensor elements,

means for converting said data, and

means for interfacing with external evaluation means.

13. The measuring and monitoring system according to claim 12, further including a power source on the sensing device and wireless means for interfacing with the external evaluation means.

14. A method for making a transducer for continuously and noninvasively measuring and monitoring blood pressure in a blood vessel, the method including the steps of:

fabricating on a single semiconductor chip with conventional semiconductor technology, preferably CMOS technology,

an array of sensor elements,

means for converting, and

means for transmitting said data to external evaluation means.