PRESSURE MEASUREMENT-BASED ISCHEMIA DETECTION
First Claim
1. A method of generating an indication of ischemia associated with a heart of a patient, comprising:
- determining an electrical depolarization to mechanical contraction delay for a ventricle of a heart;
determining whether the delay is more than an expected delay; and
generating an indication of ischemia in accordance with a determination that the delay is more than the expected delay.
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Accused Products
Abstract
In some aspects ischemia is indicated based on cardiac pressure measurements. For example, ischemia may be indicated based on an increase in an intraventricular electromechanical delay where mechanical contractions are detected by measuring pressure in a cardiac chamber. Ischemia detection also may involve obtaining timing information relating to a mechanical contraction of at least one ventricle to identify an intraventricular dyssynchrony. In this case, pressure measurements may be used to identify the timing of the mechanical contraction. Ischemia may be indicated based on a change in a time interval associated with a systolic interval of a ventricle. Ischemia also may be indicated based on an intracardiac electrogram-based indication of ischemia in conjunction with an increase in mean left atrial pressure and/or an increase in the size of a v-wave.
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Citations
20 Claims
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1. A method of generating an indication of ischemia associated with a heart of a patient, comprising:
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determining an electrical depolarization to mechanical contraction delay for a ventricle of a heart; determining whether the delay is more than an expected delay; and generating an indication of ischemia in accordance with a determination that the delay is more than the expected delay. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A method of generating an indication of ischemia associated with a heart of a patient, comprising:
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determining timing of an onset of mechanical contraction for at least one ventricle of a heart by measuring pressure associated with the at least one ventricle; identifying an intraventricular dyssynchrony in accordance with the timing of the onset of mechanical contraction for the at least one ventricle; and generating an indication of ischemia in accordance with the identification of an intraventricular dyssynchrony. - View Dependent Claims (11, 12, 13, 14, 15)
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16. A method of generating an indication of ischemia associated with a heart of a patient, comprising:
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generating an intracardiac electrogram-based indication of ischemia; detecting a change in left atrial pressure; and generating an indication of ischemia in accordance with the intracardiac electrogram-based indication of ischemia and the change in left atrial pressure. - View Dependent Claims (17, 18, 19, 20)
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Specification