Method and Apparatus for the Transdermal Administration of a Substance
First Claim
1. A delivery device for delivering a substance into a patient comprising:
- a syringe having a syringe barrel with an outlet tip and a plunger operable by manual pressure for dispensing said substance contained in said syringe;
said device includes a housing defining a fixed volume reservoir having at least a top and bottom wall;
a check valve disposed at between said syringe and said reservoir to prevent flow from said reservoir to said syringe, wherein said check valve is the only entry point for said substance into said reservoir; and
a plurality of 15-40 gauge microneedles coupled to said outlet tip and having a channel extending through the microneedles in continuous fluid communication with said reservoir for delivering the substance to a patient.
1 Assignment
0 Petitions
Accused Products
Abstract
A transdermal delivery device includes a plurality of microneedles for injecting a substance such as a pharmaceutical agent into or below the stratum corneum of the skin. The device has housing formed from a top and bottom wall to define a chamber for containing a pharmaceutical agent. An inlet port is provided in the top wall of the housing for supplying the pharmaceutical agent to the chamber and directing the agent to the microneedles. The housing can have a Luer lock type fitting for coupling with a syringe having a Luer lock collar to inject the pharmaceutical agent into the housing. The housing can be divided into a plurality of chambers by an internal wall for supplying different agents simultaneously or sequentially to a patient. The microneedles have a length of about 5-250 microns and generally about 50-100 microns.
-
Citations
20 Claims
-
1. A delivery device for delivering a substance into a patient comprising:
-
a syringe having a syringe barrel with an outlet tip and a plunger operable by manual pressure for dispensing said substance contained in said syringe; said device includes a housing defining a fixed volume reservoir having at least a top and bottom wall; a check valve disposed at between said syringe and said reservoir to prevent flow from said reservoir to said syringe, wherein said check valve is the only entry point for said substance into said reservoir; and a plurality of 15-40 gauge microneedles coupled to said outlet tip and having a channel extending through the microneedles in continuous fluid communication with said reservoir for delivering the substance to a patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
-
-
13. A device for administering a substance to the skin of a patient comprising:
-
a substantially planar base having a top surface, a bottom surface and an opening extending between said top and bottom surfaces which comprises a fixed volume reservoir; a coupling member attached to said top surface of said base for directing said substance through said openings in said base and for coupling to a fluid source, wherein said coupling member is the only entry point for said substance into said reservoir; a check valve disposed at said coupling member to prevent flow from said reservoir through said coupling member a plurality of 15-40 gauge microneedles attached to and extending from said bottom surface of said base in continuous fluid communication with said reservoir; and a plurality of channels formed in said bottom surface of said base and extending outwardly from said opening and being positioned between said microneedles. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20)
-
Specification