Nasal Delivery Devices
First Claim
1. A nasal delivery device for delivering substance to a nasal cavity of a subject, the delivery device comprising:
- a container-receiving unit comprising a container chamber for receiving a substance-containing container which contains substance to be delivered to the nasal cavity of the subject, the container chamber including an inlet and an outlet;
a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject and being in fluid communication with the outlet of the container chamber;
a mouthpiece unit including a mouthpiece in fluid communication with the inlet of the container chamber and through which the subject in use exhales, such as to entrain substance from the container and deliver the same through the nosepiece; and
a moisture-reducing element for reducing condensation at or downstream of the container chamber.
1 Assignment
0 Petitions
Accused Products
Abstract
A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a container-receiving unit comprising a container chamber for receiving a substance-containing container which contains substance to be delivered to the nasal cavity of the subject, the container chamber including an inlet and an outlet; a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject and being in fluid communication with the outlet of the container chamber; a mouthpiece unit including a mouthpiece in fluid communication with the inlet of the container chamber and through which the subject in use exhales, such as to entrain substance from the container and deliver the same through the nosepiece; and moisture-mitigation means for mitigating an effect of moisture in an exhaled breath on the entrainment of substance from the container, which means are provided, for example, by providing the container in a replaceable container-containing member, by a pressure-sensitive valve which normally closes the fluid connection between the container chamber and the mouthpiece, and a temperature regulator upstream of the container chamber.
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Citations
78 Claims
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1. A nasal delivery device for delivering substance to a nasal cavity of a subject, the delivery device comprising:
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a container-receiving unit comprising a container chamber for receiving a substance-containing container which contains substance to be delivered to the nasal cavity of the subject, the container chamber including an inlet and an outlet; a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject and being in fluid communication with the outlet of the container chamber; a mouthpiece unit including a mouthpiece in fluid communication with the inlet of the container chamber and through which the subject in use exhales, such as to entrain substance from the container and deliver the same through the nosepiece; and a moisture-reducing element for reducing condensation at or downstream of the container chamber. - View Dependent Claims (2, 4, 6, 8, 10, 11, 12, 14, 15, 16, 17, 19, 21, 23, 25, 26, 27, 28, 29, 31, 32, 33)
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3. (canceled)
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5. (canceled)
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7. (canceled)
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9. (canceled)
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13. (canceled)
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18. (canceled)
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20. (canceled)
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22. (canceled)
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24. (canceled)
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30. (canceled)
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34. (canceled)
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35. A nasal delivery device for delivering substance to a nasal cavity of a subject, the delivery device comprising:
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a container-receiving unit comprising a container chamber for receiving a substance-containing container which contains substance to be delivered to the nasal cavity of the subject, the container chamber including an inlet and an outlet; a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject and being in fluid communication with the outlet of the container chamber; a mouthpiece unit including a mouthpiece in fluid communication with the inlet of the container chamber and through which the subject in use exhales, such as to entrain substance from the container and deliver the same through the nosepiece. - View Dependent Claims (36, 38, 40, 42, 44, 45, 46, 48, 49, 50, 51, 53, 55, 57, 59, 60, 61, 62, 63, 65, 66, 67)
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37. (canceled)
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39. (canceled)
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41. (canceled)
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43. (canceled)
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47. (canceled)
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52. (canceled)
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54. (canceled)
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56. (canceled)
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58. (canceled)
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64. (canceled)
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68. (canceled)
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69. A nasal delivery device for delivering substance to a nasal cavity of a subject, the delivery device comprising:
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a body member; a carrier which is supported by the body member and carries a plurality of substance-containing containers; a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject; a mouthpiece unit including a mouthpiece through which the subject in use exhales; and an actuating mechanism which is operative, in each operation, to open a plurality of the substance-containing containers, and including a valve unit for fluidly connecting the mouthpiece to a respective one of the opened substance-containing containers in successive exhalation cycles. - View Dependent Claims (70, 71, 72, 73, 74)
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75. (canceled)
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76. A method of delivering substance to a nasal cavity of a subject, the method comprising the steps of:
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disposing a substance-containing container which contains substance to be delivered to the nasal cavity of the subject in a container chamber, the container chamber including an inlet and an outlet; fitting a nosepiece in fluid communication with the outlet of the container chamber to a nasal cavity of the subject; the subject exhaling through a mouthpiece which is in fluid communication with the inlet of the container chamber, such as to deliver an air flow through the container chamber and entrain substance from the container and deliver the same through the nosepiece and into the nasal cavity of the subject; and drawing moisture from the exhaled air flow upstream of the container chamber, such as to reduce condensation at or downstream of the container chamber.
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77. A method of delivering substance to a nasal cavity of a subject, the method comprising the steps of:
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disposing a substance-containing container which contains substance to be delivered to the nasal cavity of the subject in a container chamber, the container chamber including an inlet and an outlet; fitting a nosepiece in fluid communication with the outlet of the container chamber to a nasal cavity of the subject; and the subject exhaling through a mouthpiece which is in fluid communication with the inlet of the container chamber, such as to deliver an air flow through the container chamber and entrain substance from the container and deliver the same through the nosepiece and into the nasal cavity of the subject.
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78. (canceled)
Specification