Umbilical Cord Stem Cell Composition & Method of Treating Neurological Diseases
First Claim
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1. A method of treating a neurological disease comprising the step of administering to a patient a therapeutically effective amount of a composition including stem cells derived from an umbilical cord.
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Abstract
A neurological disease is treated by administering to a patient a therapeutically effective amount of a composition including human umbilical cord stem cells. The composition may include growth factors mixed with the stem cells immediately prior to being administered. A specific pre and post transplantation protocol provides optimal methods for obtaining favorable clinical results.
33 Citations
40 Claims
- 1. A method of treating a neurological disease comprising the step of administering to a patient a therapeutically effective amount of a composition including stem cells derived from an umbilical cord.
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22. A method of treating cerebral palsy or traumatic brain injury comprising the step of administering to a patient a dose of at least 1 million umbilical cord stem cells of which at least substantially 85% of the cells are selected from the group consisting of CD133+ umbilical cord stem cells, CD44−
- umbilical cord stem cells, CD45−
umbilical cord stem cells, CD34−
/45+ umbilical cord stem cells, CD34−
/45−
umbilical cord stem cells, and mesenchymal umbilical cord stem cells. - View Dependent Claims (23, 24)
- umbilical cord stem cells, CD45−
- 25. A composition of matter comprising a mixture of human umbilical cord stem cells and growth factors mixed with the stem cells substantially immediately prior to administration of a single dose of the composition to a patient.
- 35. A composition of matter comprising a mixture of human umbilical cord stem cells and blood plasma.
Specification