Model-Based Flow Analysis and Visualization
First Claim
1. A method (100) for analyzing blood flow in a vascular system from a diagnostic observation thereof, comprising the steps of:
- providing a database (602) of at least one exemplary blood flow model of a vascular system, the at least one model having an associated parameter set of the most relevant blood flow parameters of the modeled vascular system;
providing a diagnostic observation (101) as a sequence of at least two images that show the advance of contrast agent in the vascular system;
extracting a set of extracted quantitative blood flow features (102) of the vascular system using the parameter set of the model, from the provided diagnostic observation (101);
selecting (103) and linking at least one blood flow model (603) for the observed vascular system from the database (602) such that predicted flow blood features (108) predicted by the model match the extracted blood flow features (102) according to a pre-determined matching function of the associated set of blood flow parameters; and
outputting the model and the associated parameter set of blood flow parameters.
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Abstract
A system (900), method (100, 200) and apparatus (600, 700, 800) are provided for analyzing a blood flow in a vascular system from a dynamic diagnostic observation sequence (101) to determine blood flow parameters (112) for further determination of filters, replay speed and finally visualization of the replayed original and filtered sequences. A first embodiment (100) extracts features of the observation and uses these features to select an appropriate model from a database of pre-determined models of vascular system of interest which have associated parameters. These parameters are varied to create an instance of the model that best matches the original observation. A second embodiment (200) visualizes a replay of the original observation (101) and the observation (101′) predicted by the model to highlight differences therebetween. A third embodiment (800) provides filtering and control of the replay speed.
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Citations
35 Claims
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1. A method (100) for analyzing blood flow in a vascular system from a diagnostic observation thereof, comprising the steps of:
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providing a database (602) of at least one exemplary blood flow model of a vascular system, the at least one model having an associated parameter set of the most relevant blood flow parameters of the modeled vascular system; providing a diagnostic observation (101) as a sequence of at least two images that show the advance of contrast agent in the vascular system; extracting a set of extracted quantitative blood flow features (102) of the vascular system using the parameter set of the model, from the provided diagnostic observation (101); selecting (103) and linking at least one blood flow model (603) for the observed vascular system from the database (602) such that predicted flow blood features (108) predicted by the model match the extracted blood flow features (102) according to a pre-determined matching function of the associated set of blood flow parameters; and outputting the model and the associated parameter set of blood flow parameters. - View Dependent Claims (2, 3, 4, 5, 6, 9, 10, 11, 12, 16, 17, 18, 19, 20, 21, 22, 23, 24, 26, 30)
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- 8. The method (100) of claim 8, further comprising the step of presenting the flow parameters to the user.
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13. The method (100) of claim 13, wherein the aneurysm sac comprises two parallel tubular vessels, one for the parenting vessel and one replacing the aneurysm itself.
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14. The method (100) of claim 14, wherein the aneurysm sac comprises a fluid chamber with homogenous contrast concentration.
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15. An apparatus (600) for analyzing blood flow in an observed vascular system from a diagnostic observation (101) thereof, comprising:
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a database (602) of exemplary models of blood flow in vascular systems, each model having an associated set of blood flow parameters most relevant to the modeled vascular system; and a model instance generator (600) to control creation of an instance of at least one exemplary model selected from the database (602) based on extracted features (102) of the observed vascular system and linked such that predicted blood flow features (108) predicted by the at least one model match extracted blood flow features (102) according to a pre-determined matching function of the associated set of blood flow parameters. - View Dependent Claims (25, 31, 32, 33, 34)
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27. A method for filtering a dynamic diagnostic observation sequence showing the advance of a contrast agent in a vascular system therein, comprising the steps of:
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locally determining the strength of a temporal filter based on at least one criteria selected from the group consisting of; a local blood velocity of the diagnostic observation, and a blur due to filtering that only covers a pre-defined distance that the contrast agent can pass over in an observation time defined by a filter scale; determining a global filter strength from the locally determined filter strengths by minimum comparison; and applying a pre-determined number of filters selected from the group consisting of a temporal filter and a global filter to the observation. - View Dependent Claims (28, 29)
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35. A system (900) for filtering replaying and visualizing a dynamic observation sequence (101), comprising:
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a filter module (800) to determine at least one filter from flow parameters (112) of the dynamic observation sequence and replay at a determined speed the filtered dynamic observation sequence (101); a flow analysis module operably connected to the filter module (800) to determine flow parameters (112) of the dynamic observation sequence and provide said determined flow parameters to the flow analysis module (800); and a visualization system (700) operably connected to the filter module to visualize at least one of a replay of the filtered sequence and a replay of the observation.
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Specification