Amniotic membrane preparations and purified compositions and therapy for scar reversal and inhibition
First Claim
1. A method for inhibiting scar formation in a subject comprising the step of providing an effective amount of a scar formation inhibition composition to a subject in need of scar formation inhibition;
- wherein the scar formation inhibition composition comprises at least one component prepared from a human amniotic material selected from a human amniotic membrane, a human amniotic jelly, a human amniotic stroma, or a combination thereof extracted from an amniotic membrane.
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Accused Products
Abstract
Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues. Placental amniotic membrane (AM) preparations described herein include AM pieces, AM extracts, AM jelly, AM stroma, and mixtures of these compositions with additional components. The compositions can be used to treat various diseases, such as wound healing, inflammation and angiogenesis-related diseases.
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Citations
10 Claims
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1. A method for inhibiting scar formation in a subject comprising the step of providing an effective amount of a scar formation inhibition composition to a subject in need of scar formation inhibition;
- wherein the scar formation inhibition composition comprises at least one component prepared from a human amniotic material selected from a human amniotic membrane, a human amniotic jelly, a human amniotic stroma, or a combination thereof extracted from an amniotic membrane.
- View Dependent Claims (2, 3, 4, 5)
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6. A method for reversing scar formation in a subject comprising the step of providing an effective amount of a scar reversal composition to a scarred subject;
- wherein the scar reversal composition comprises at least one component prepared from a human amniotic material selected from a human amniotic membrane, a human amniotic jelly, a human amniotic stroma, or a combination thereof extracted from an amniotic membrane.
- View Dependent Claims (7, 8, 9, 10)
Specification