UVEOSCLERAL DRAINAGE DEVICE

• US 20080306429A1
• Filed: 06/09/2008
• Published: 12/11/2008
• Est. Priority Date: 06/07/2007
• Status: Abandoned Application

• Current Assignee: Vidus Ocular, Inc. (Opko Health, Inc.), Yale University
• Original Assignee: Yale University
• Inventors: Shields, Milton B., Warner, Nicholas Fish, Bronstein, Ben
• Application Number:
  US12/135,848
• Publication Number:
  US 20080306429A1
• Time in Patent Office: Days
• US Class Current: 604/8
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

An ophthalmic shunt implantable in an eye has an elongate body and a conduit for conducting aqueous humor from an anterior chamber of the eye to the suprachoroidal space of the eye. The elongate body has a forward end, a spaced back end, and an insertion head that extends from the forward end. The insertion head defines a shearing edge suitable for cutting eye tissue engage thereby. The elongate body can define at least one slot that is configured for operative receipt of a surgical tool such as an obturator. In another aspect, at least a portion of the conduit can be configured for operative receipt of a surgical tool such as an obturator.

Claims

1. An ophthalmic shunt implantable in an eye, comprising:

an elongate body having a forward end, a back end, and a tapered insertion head extending from the forward end of the elongate body, the insertion head defining a shearing edge constructed and arranged for cutting eye tissue engaged thereby, the forward end and the insertion head of said body further defining a shoulder surface; and

a conduit having a first end defined at the shearing edge of said insertion head and extending through said body from the forward end to the back end thereof, the first;

wherein the elongate body is configured to position at least a portion of the insertion head and the first end of the conduit through an incision formed by the shearing edge of the insertion head and into fluid communication with the anterior chamber of the eye and to seat at least a portion of the insertion head against the incision.

2. The shunt of claim 1, wherein the elongate body has a substantially fusiform cross-sectional shape.

3. The shunt of claim 1, wherein the elongate body has a lower surface, and wherein a portion of the insertion head is substantially co-planar to the lower surface thereof.

4. The shunt of claim 1, wherein the elongate body has an arcuate shape along at least a portion of its length that is adapted to extend along the curvature of the sclera.

5. The shunt of claim 1, wherein the conduit is configured to receive at least a portion of an obtruator.

6. The shunt of claim 5, wherein a first end of the obturator is at least flush with the first end of the conduit.

7. The shunt of claim 1, wherein the first end of the conduit is positioned at an acute angle with respect to the insertion head.

8. The shunt of claim 1, wherein the elongate body has at least one suture hole configured to facilitate suturing the elongate body to eye tissue.

9. The shunt of claim 1, wherein the elongate body has a first elongate edge and a spaced second elongate edge, and wherein said body has at least a pair of spaced suture holes configured to facilitate suturing the elongate body to eye tissue, one suture hole of the pair of spaced suture holes being defined in each respective elongate edge.

10. The shunt of claim 1, wherein the elongate body has an upper surface and a spaced lower surface, and wherein the body has at least a pair of spaced suture holes extending between the upper and lower surfaces of said elongate body, the pair of spaced suture holes configured to facilitate suturing the elongate body to eye tissue.

11. An ophthalmic shunt assembly, comprising:

an elongate body having a forward end, a back end, and an insertion head extending from the forward end of the elongate body, the insertion head defining a shearing edge constructed and arranged for cutting eye tissue engaged thereby, the forward end and the insertion head of said body further defining a shoulder surface;

a conduit having a first end defined at the shearing edge of said insertion head and extending through said body from the forward end to the back end thereof; and

an obturator,

wherein the conduit is configured to receive at least a portion of the obturator, and

wherein the elongate body is configured to position at least a portion of the insertion head and the first end of the conduit through an incision formed by the shearing edge of the insertion head and into fluid communication with the anterior chamber of the eye and to seat at least a portion of the insertion head against the incision.

12. The shunt assembly of claim 12, wherein the elongate body has a substantially fusiform cross-sectional shape.

13. The shunt assembly of claim 12, wherein a first end of the obturator is at least flush with the first end of the conduit.

14. The shunt assembly of claim 12, wherein the obturator further comprises a handle located at an opposing end of the first end of the obturator.

15. The shunt assembly of claim 12, wherein the elongate body has at least one suture hole configured to facilitate suturing the elongate body to eye tissue.

16. The shunt assembly of claim 12, wherein the elongate body has a first elongate edge and a spaced second elongate edge, and wherein said body has at least a pair of suture holes configured to facilitate suturing the elongate body to eye tissue, one suture hole of the pair of suture holes being defined in each respective elongate edge.

17. The shunt assembly of claim 12, wherein the conduit comprises a valve.

18. The shunt assembly of claim 12, wherein a first end of the conduit is positioned at an acute angle with respect to the insertion head.

19. The shunt assembly of claim 12, wherein the conduit comprises at least a rigid front end.

20. The shunt assembly of claim 12, wherein the elongate body further comprises a flexible tube in fluid communication with the conduit to provide a channel for fluid flow from an anterior space to a suprachoroidal space.

22. The shunt assembly of claim 12, wherein the assembly delivers at least one therapeutic agent to a suprachoroidal space.

21. The shunt assembly of claim 21, wherein a posterior end of the conduit comprises at least one of a plurality of filaments, wires or hollow structures.

23. A method for treating glaucoma in an eye, comprising:

a. providing a biocompatible ophthalmic shunt, wherein the ophthalmic shunt comprises;

i. an elongate body having a forward end, a back end, and a tapered insertion head extending from the forward end of the elongate body, the insertion head defining a shearing edge constructed and arranged for cutting eye tissue engaged thereby, the forward end and the insertion head of said body further defining a shoulder surface; and

ii. a conduit having a first end defined at the shearing edge of said insertion head and extending through said body from the forward end to the back end thereof;

wherein the elongate body is configured to position at least a portion of the insertion head and the first end of the conduit through an incision formed by the shearing edge of the insertion head and into fluid communication with the anterior chamber of the eye and to seat at least a portion of the insertion head against the incision to seal the incision;

b. inserting at least a portion of the shearing edge of the insertion head of the shunt into and through an anterior chamber angle and into the anterior chamber of the eye, with the first end of the conduit into fluid communication with the anterior chamber of the eye;

c. introducing the insertion head anteriorally to seat the shoulder surface of the implant adjacent an interior surface of a supraciliary space of the eye;

d. disposing the back end of the elongate body of the shunt into a suprachoroidal space of the eye so that a second end of the conduit is in fluid communication with the suprachoroidal space;

e. securing the shunt to the eye.

24. The method of claim 24, further comprising, prior to the insertion of the insertion head into the anterior chamber making a first incision in and through the conjunctiva and the sclera at a position posterior to the limbus.

25. The method of claim 24, further comprising delivering at least one therapeutic agent to a suprachoroidal space.