Composition and Methods for Skin Care
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0 Petitions
Accused Products
Abstract
Compositions useful in the treatment of skin atrophy and improvement of skin appearance and texture are disclosed. The methods include the topical administration of vitamin D3 or specific vitamin D3 analogs as an essential ingredient either on its own or in combination with cADPR and or nicotinamide. The compositions are particularly effective in preventing and treating signs of chronological and or photoaging including fine lines, wrinkles and discoloration.
30 Citations
47 Claims
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1-23. -23. (canceled)
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24. A method for preventing, retarding, arresting, or reversing atrophy in skin of a mammalian subject in need thereof, the method comprising the step of:
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topically applying to the skin of the subject a dermatologically effective amount of a composition comprising;
a first active agent selected from the group consisting of vitamin D3 and a vitamin D3 analog;
a second active agent selected from the group consisting of cyclic adenosine diphosphate-ribose (cADPR), a cADPR analog, nicotinamide, and a nicotinamide analog; and
a dermatologically acceptable carrier,thereby preventing, retarding, arresting, or reversing atrophy in the skin of the subject. - View Dependent Claims (25, 26, 27, 28, 29)
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30. A method of preventing or treating an epidermal condition related to aging in a subject in need thereof, the method comprising the step of:
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topically administering to the skin of the subject a dermatologically effective amount of a composition comprising;
a first active agent selected from the group consisting of vitamin D3 and a vitamin D3 analog;
a second active agent selected from the group consisting of cyclic adenosine diphosphate-ribose (cADPR), a cADPR analog, nicotinamide, and a nicotinamide analog; and
a dermatologically acceptable carrier,thereby preventing or treating an epidermal condition related to aging in the subject. - View Dependent Claims (31, 32, 33, 34, 35, 36)
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37. A method of preventing or treating an epidermal condition related to aging in a subject in need thereof, the method comprising the step of:
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topically administering to the skin of the subject a dermatologically effective amount of a composition consisting essentially of a first active agent selected from the group consisting of vitamin D3 and a vitamin D3 analog;
a second active agent selected from the group consisting of nicotinamide and a nicotinamide analog; and
a dermatologically acceptable carrier,thereby preventing or treating an epidermal condition related to aging in the subject. - View Dependent Claims (38, 39, 40)
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41. A method of preventing or treating an epidermal condition related to aging in a subject in need thereof, the method comprising the step of:
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topically administering to the skin of the subject a dermatologically effective amount of a composition consisting essentially of;
a first active agent selected from the group consisting of vitamin D3 and a vitamin D3 analog;
a second active agent selected from the group consisting of cyclic adenosine diphosphate-ribose (cADPR) and a cADPR analog;
a third active agent selected from the group consisting of nicotinamide and a nicotinamide analog; and
a dermatologically acceptable carrier,thereby preventing or treating an epidermal condition related to aging in the subject. - View Dependent Claims (42, 43, 44, 45)
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46. A method of preventing or treating an epidermal condition related to aging in a subject in need thereof, the method comprising the step of:
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topically administering to the skin of the subject a dermatologically effective amount of a composition consisting essentially of an active agent selected from the group consisting of calcipotriol and calcitriol; and
a dermatologically acceptable carrier,thereby preventing or treating an epidermal condition related to aging in the subject. - View Dependent Claims (47)
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Specification