Injection Device

• US 20080312591A1
• Filed: 05/27/2005
• Published: 12/18/2008
• Est. Priority Date: 05/28/2004
• Status: Active Grant

• Current Assignee: Cilag Gmbh International (Johnson & Johnson)
• Original Assignee: Cilag Gmbh International (Johnson & Johnson)
• Inventors: Harrison, Nigel
• Granted Patent: US 9,675,757 B2
• Time in Patent Office: Days
• US Class Current: 604/135
• CPC Class Codes: A61M 2005/202 cocking means, e.g. to bias the main drive spring of an injector
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/3261 triggered by radial deflection of the anchoring parts between sleeve and syringe barrel, e.g. spreading of sleeve retaining hooks having slanted surfaces by engagement with conically shaped collet of the piston rod during the last portion of the injection stroke of the plunger
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/3204 Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
• CPC Class Codes: A61M 5/326 Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user

Abstract

An injection device (210) is described. A housing (212) receives a syringe and includes a return spring (226) for biasing the syringe from an extended position in which its needle (218) extends from the housing (212) to a retracted position in which the it does not. A drive spring (230) acts on a first drive element (232) and a second drive element (234) acts upon the syringe to advance it from its retracted position to its extended position and discharge its contents through the needle. The first drive element (232) is capable of movement relative to the second (234) once a nominal decoupling position has been reached. A release mechanism is activated when the first drive element (234) is further advanced to a nominal release position, to release the syringe (214) from the action of the drive spring (230), whereupon the return spring (226) restores the syringe (214) to its retracted position. Decoupling of the drive elements is achieved with a particular form of releasable drive coupling using two pairs of overlying flexible arms (235, 247). A particular form of release mechanism that also uses flexible arms (233) is also envisaged.

Claims

1. A releasable drive coupling for an injection device comprising:

a first drive element having a first projecting flexible arm; and

a second drive element capable of sliding relative to the first drive element and having;

a drive surface adapted to receive the first flexible arm, to allow axial loads to be transmitted from one drive element to the other; and

a second projecting flexible arm so positioned relative to the drive surface that inward flexing of the second flexible arm causes it to act upon the first flexible arm and flex the latter to a point at which it is no longer received by the drive surface, at which point the first and second drive elements are free to slide relative to one another and the drive coupling is thus disengaged.

2. A coupling according to claim 1 in which the first flexible arms operate in compression to transmit axial loads from one drive element to the other.

3. A coupling according to claim 1 in which:

the first drive element is an inner drive element;

the first flexible arm projects outwardly from the inner drive element;

the second drive element is an outer drive element capable of sliding over the inner drive element;

the second flexible arm projects outwardly from the outer drive element; and

inward flexing of the outer flexible arm causes it to flex the inner flexible arm inwardly.

4. A coupling according to claim 3 in which the outer drive element has a bore in which the inner drive element is received.

5. A coupling according to claim 3 in which:

the inner drive element has a plurality of outwardly projecting, inner flexible arms; and

the outer drive element has a corresponding plurality of drive surfaces and a corresponding plurality of outwardly projecting, outer flexible arms.

6. A coupling according to claim 5 in which the outwardly projecting, inner flexible arms are substantially equidistantly spaced around the circumference of the inner drive element.

7. A coupling according to claim 6 comprising exactly two, diametrically opposite inner flexible arms.

8. A coupling according to claim 5 in which the outwardly projecting, outer flexible arms are substantially equidistantly spaced around the circumference of the outer drive element.

9. A coupling according to claim 7 comprising exactly two, diametrically opposite outer flexible arms.

10. An automatically releasable drive coupling for an injection device comprising:

a releasable drive coupling according to any preceding claim;

an actuator acting upon one of the drive components; and

a decoupling component so arranged that, as the second drive element is advanced by the actuator, it flexes the second flexible arm inwardly, automatically disengaging the drive coupling.

11. A coupling according to claim 10 in which the decoupling component comprising a channel through which the first and second drive elements pass when acted upon by the actuator, the channel being so arranged that, as the second drive element passes through it, it flexes the second flexible arm inwardly, automatically disengaging the drive coupling.

12. An injection device comprising:

a housing adapted to receive a syringe having a discharge nozzle, the housing including means for biasing the syringe from an extended position in which the discharge nozzle extends from the housing to a retracted position in which the discharge nozzle is contained within the housing;

an automatically releasable drive coupling according to claim 10 or claim 11 in which;

the first drive element is acted upon by the actuator and the second drive element acts upon the syringe to advance it from its retracted position to its extended position and discharge its contents through the discharge nozzle; and

the decoupling component automatically disengages the drive coupling when the drive elements have been advanced to a nominal decoupling position.

13. An injection device according to claim 12, further comprising:

a release mechanism, activated when the first drive element has been advanced to a nominal release position that is more advanced than the said nominal decoupling position, and adapted to release the syringe from the action of the actuator, whereupon the biasing means restores the syringe to its retracted position.

14. An injection device according to claim 13 in which the nominal release position is defined by the actuator interacting with the first drive element once the nominal decoupling position has been reached, at which position the first drive element is restrained by the syringe against further movement.

15. An injection device according to claim 13 in which the release mechanism is adapted to decouple the first drive element from the actuator once the said nominal release position has been reached, thus releasing the syringe from the action of the actuator.

16. An injection device according to claim 13 further comprising a second coupling, between the actuator and the first drive element, that prevents the actuator from moving relative to the first drive element until the nominal release position has been reached.

17. An injection device according to claim 16 in which the second coupling comprises cooperating features of the actuator and the first drive element allowing the former to act upon the latter.

18. An injection device comprising:

a housing adapted to receive a syringe having a discharge nozzle, the housing including means for biasing the syringe from an extended position in which the discharge nozzle extends from the housing to a retracted position in which the discharge nozzle is contained within the housing;

an actuator;

first and second drive elements, of which the first is acted upon by the actuator and in turn acts upon the second, and the second acts upon the syringe to discharge its contents through the discharge nozzle, the first drive element being capable of movement relative to the second when the first is acted upon by the actuator and the second is restrained by the syringe;

of the actuator and the first drive element, one comprises a flexible arm that engages with a drive surface on the other, allowing the actuator to act upon the first drive element and preventing the former from moving relative to the latter; and

the second drive element comprises a stop that prevents the flexible arm disengaging from the drive surface until the first drive element has been advanced to a nominal release position relative to the second, whereupon the flexible arm disengages from the drive surface, allowing the actuator to move relative to the first drive element and thus releasing the syringe from the action of the actuator, whereupon the biasing means restores the syringe to its retracted position.

19. An injection device according to claim 18 in which the second drive element advances the syringe from its retracted position to its extended position.

21. An injection device according to claim 18, in which the action of the actuator tends to disengage the flexible arm from the drive surface, but is prevented from doing so until the said nominal release position has been reached.

22. An injection device according to claim 18 in which the flexible arm includes a detent and the stop is in register with the detent when the said nominal release position is reached, thus allowing the flexible arms to flex.

23. An injection device according to claim 21 in which the flexible arm is biased toward a position at which it engages the second drive surface and the action of the actuator causes it to move against its bias, thus disengaging it from the drive surface.

24. An injection device according to any one of claims 18-23 in which the said one of the actuator and the first drive element is the first drive element.

25. An injection device according to claim 21 in which the said one of the actuator and the first drive element comprises a plurality of such flexible arms.

26. An injection device according to claim 18 in which:

the releasable coupling comprises cooperating features of the first and second drive elements that allow the first to act upon the second.

27. An injection device according to claim 26 in which the cooperating features include flexible arms on one of the drive elements that engage with a drive surface on the other.

28. An injection device according to claim 26 in which the coupling comprises a decoupling mechanism, activated when the drive elements have been advanced to the said nominal decoupling position and adapted to decouple the inner drive element from the outer, thus allowing the first drive element to move relative to the second.

29. An injection device according to claim 26, in which:

the releasable coupling comprises flexible arms on one of the drive elements that engage with a drive surface on the other; and

the decoupling component causes the flexible arms to move when the said nominal decoupling position is reached, by acting on an intermediate component, thus disengaging the flexible arms from the drive surface to allow the first drive element to move relative to the second.

30. An injection device according to claim 29 in which the intermediate component is a flexible component of the drive element upon which the said drive surface is to be found.

31. An injection device according to claim 27 in which the flexible arms are biased toward a position at which they engage the drive surface and the decoupling component causes them to move against their bias, thus disengaging them from the drive surface.

20. An injection device comprising:

a housing adapted to receive a syringe having a discharge nozzle, the housing including means for biasing the syringe from an extended position in which the discharge nozzle extends from the housing to a retracted position in which the discharge nozzle is contained within the housing;

an actuator;

a drive, acted upon by the actuator and acting upon the syringe to discharge its contents through the discharge nozzle; and

of the actuator and the drive, one comprises a flexible arm that engages with a drive surface on the other, allowing the actuator to act upon the drive and preventing the former from moving relative to the latter;

in which the flexible arm is prevented from disengaging from the drive surface until the drive has been advanced to a nominal release position, whereupon the flexible arm disengages from the drive surface, allowing the actuator to move relative to the drive and thus releasing the syringe from the action of the actuator, whereupon the biasing means restores the syringe to its retracted position.