Radiation treatment planning and delivery for moving targets in the heart
First Claim
1. A method of radiating a moving target inside a heart, the method comprising:
- A acquiring sequential volumetric representations of an area of the heart;
B defining a target tissue region and/or a radiation sensitive structure region in 3-dimensions (3D) for a first of the representations;
C identifying the target tissue region and/or radiation sensitive structure region for another of the representations by an analysis of the area of the heart from the first representation and the other representation; and
D firing radiation beams to the target tissue region in response to the identified target tissue region and/or radiation sensitive structure region from the other representation.
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Accused Products
Abstract
Method and systems are disclosed for radiating a moving target inside a heart. The method includes acquiring sequential volumetric representations of an area of the heart and defining a target tissue region and/or a radiation sensitive structure region in 3D for a first of the representations. The target tissue region and/or radiation sensitive structure region are identified for another of the representations by an analysis of the area of the heart from the first representation and the other representation. Radiation beams to the target tissue region are fired in response to the identified target tissue region and/or radiation sensitive structure region from the other representation.
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Citations
51 Claims
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1. A method of radiating a moving target inside a heart, the method comprising:
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A acquiring sequential volumetric representations of an area of the heart; B defining a target tissue region and/or a radiation sensitive structure region in 3-dimensions (3D) for a first of the representations; C identifying the target tissue region and/or radiation sensitive structure region for another of the representations by an analysis of the area of the heart from the first representation and the other representation; and D firing radiation beams to the target tissue region in response to the identified target tissue region and/or radiation sensitive structure region from the other representation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A method of radiating a moving target of a wall of a heart, the method including the steps of:
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A acquiring at least one volume of the heart; B defining the target tissue region and/or critical structure region in 3D so that the target tissue region extends through the wall of the heart; C computing a dose distribution; and D firing radiation beams to the target to obtain the simulated dose distribution transmurally through the wall of the heart. - View Dependent Claims (15, 16, 17, 18, 19, 20)
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21. A method of radiating a moving target inside the heart, the method comprising:
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A acquiring a computed tomography (CT) volume; B defining a transmural target tissue region; C computing a dose distribution; D visualizing the dose distribution using volume or surface rendering in 3-dimensions (3D) so as to verify transmurality; and E. delivering the dose using radiation beams to the transmural target tissue region. - View Dependent Claims (22, 23, 24, 25)
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26. A system for radiating a moving target inside a heart, the system comprising:
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a volume acquisition system for acquiring at least one computed tomography (CT) volume of an area of the heart; a processor coupled to the volume acquisition system, the processor configured for; defining the target tissue region and/or critical structure region in 3-dimensions (3D); computing a dose distribution; a robot coupled to the processor; and a radiation beam source supported by the robot and coupled to the processor; the processor being configured with machine-readable code embodying instructions for firing a series of the radiation beams from the radiation source so as to treat the target tissue region. - View Dependent Claims (27, 28, 29)
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30. A system for radiating a moving target of a wall of a heart, the system comprising:
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a volume acquisition system for acquiring a computed tomography (CT) volume; a processor coupled to the volume acquisition system, the processor configured for; defining a transmural target tissue region; computing a dose distribution; and a visualization system for visualizing the dose distribution using volume or surface rendering in 3-dimensions (3D) so as to verify transmurality. - View Dependent Claims (31, 32)
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33. A method of radiating a moving target inside a heart, the method comprising:
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A acquiring sequential volumetric representations of an area of the heart; B defining a target tissue region and/or a radiation sensitive structure region in 3-dimensions (3D); C expanding the target tissue region and/or a radiation sensitive structure region with a margin based on a motion of the target tissue region and/or the radiation sensitive structure region; and D firing radiation beams to the target tissue region in response based on the margin. - View Dependent Claims (34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44)
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45. A system for radiating a moving target inside a heart, the system comprising:
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a volume acquisition system for acquiring sequential volumetric representations of an area of the heart; a processor coupled to the image acquisition system, the processor configured for; defining the target tissue region and/or critical structure region in 3-dimensions (3D); expanding the target tissue region and/or a radiation sensitive structure region with a margin based on a motion of the target tissue region and/or the radiation sensitive structure region; computing a dose distribution; a robot coupled to the processor; and a radiation beam source supported by the robot and coupled to the processor; the processor being configured with machine-readable code embodying instructions for firing a series of the radiation beams from the radiation source so as to treat the target tissue region based on the margin. - View Dependent Claims (46, 47, 48, 49, 50, 51)
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Specification