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Methods for making character strings, polynucleotides and polypeptides having desired characteristics

  • US 20080318795A1
  • Filed: 10/31/2007
  • Published: 12/25/2008
  • Est. Priority Date: 01/19/1999
  • Status: Active Grant
First Claim
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1. A method of generating nucleic acids, the method comprising:

  • inputting a plurality of amino acid sequence character strings into a digital system; and

    translating the amino acid character strings in the digital system into a plurality of nucleic acid character strings, wherein translated nucleic acid sequences are selected for one or more of;

    species codon bias in a selected expression host, and optimized sequence similarity between the plurality of nucleic acid character strings.

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