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INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE DELIVERY OF MACROMOLECULES AND WATER-SOLUBLE DRUGS

  • US 20090004246A1
  • Filed: 06/26/2008
  • Published: 01/01/2009
  • Est. Priority Date: 06/26/2007
  • Status: Active Grant
First Claim
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1. An intravaginal drug delivery device comprising:

  • (a) a device body comprising a hydrophobic carrier material having at least one channel defining at least one opening to an exterior of said device body, said at least one channel being adapted to receive at least one drug-containing insert; and

    (b) at least one drug-containing insert positioned in said at least one channel, said drug-containing insert being capable of releasing a pharmaceutically effective amount of at least one drug suitable for intravaginal administration and containing at least one water-soluble release enhancer in an amount ranging from about 1% to about 70% by weight of said at least one drug-containing insert, said at least one drug and said at least one water-soluble release enhancer being dispersed in an insert carrier material;

    wherein said hydrophobic carrier material and said insert carrier material may be the same or different; and

    wherein said at least one drug-containing insert is exposed on said exterior of said device body when said intravaginal drug delivery device is in use.

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