Reinforced composite implant

• US 20090004455A1
• Filed: 06/27/2007
• Published: 01/01/2009
• Est. Priority Date: 06/27/2007
• Status: Abandoned Application

• Current Assignee: Sofradim Production SAS (Medtronic Plc)
• Original Assignee: Sofradim Production SAS (Medtronic Plc)
• Inventors: Lecuivre, Julie, Bayon, Yves, Gravagna, Philippe, Meneghin, Alfredo, Dassonville, Dagmar
• Application Number:
  US11/823,284
• Publication Number:
  US 20090004455A1
• Time in Patent Office: Days
• US Class Current: 428/304.400
• CPC Class Codes: A61L 27/24 Collagen
• CPC Class Codes: A61L 27/48 with macromolecular fillers
• CPC Class Codes: A61L 27/56 Porous materials, e.g. foams or sponges
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: A61L 31/129 containing macromolecular fillers
• CPC Class Codes: A61L 31/146 Porous materials, e.g. foams or sponges
• CPC Class Codes: A61L 31/148 Materials at least partially resorbable by the body
• CPC Class Codes: B32B 2260/04 Impregnation, embedding, or binder material
• CPC Class Codes: B32B 2262/0276 Polyester fibres
• CPC Class Codes: B32B 2266/06 Open cell foam
• CPC Class Codes: B32B 2307/5825 Tear resistant
• CPC Class Codes: B32B 5/245 another layer next to it being a foam layer
• CPC Class Codes: B32B 7/02 Physical, chemical or physicochemical properties
• CPC Class Codes: B32B 9/02 comprising animal or vegetable substances , e.g. cork, bamboo, starch
• CPC Class Codes: B32B 9/04 comprising such particular substance as the main or only constituent of a layer, which is next to another layer of the same or of a different material next to a glass layer B32B17/06; layered products with at least two ceramic layers composed mainly of ceramic B32B18/00
• CPC Class Codes: Y10T 428/249953 Composite having voids in a component [e.g., porous, cellular, etc.]
• CPC Class Codes: Y10T 442/10 Scrim [e.g., open net or mesh, gauze, loose or open weave or knit, etc.]

Abstract

Multilayer structures including a porous layer and a non-porous layer having a reinforcement member are useful as implants.

Claims

1. An implant comprising

a foam layer comprising a collagenic constituent joined to a fiber-reinforced film comprising from about 25% to about 90% collagen.

8. An implant as in claim 1 wherein the foam layer comprises Type I porcine collagen.

9. An implant as in claim 1 wherein the foam layer comprises lyophilized atelocollagen.

10. An implant as in claim 1 wherein the fiber reinforced film comprises a film reinforced with a mesh.

11. An implant as in claim 1 wherein the foam layer has haemostatic properties.

12. An implant as in claim 1 wherein the foam layer is at least about 0.1 cm thick.

13. An implant as in claim 1 wherein the foam layer is from about 0.2 to about 1.5 cm thick.

14. An implant as in claim 1 wherein the foam layer further comprises non-denatured collagen.

15. An implant as in claim 1 wherein the foam layer has a density less than about 75 mg collagen/cm².

16. An implant as in claim 1 wherein the foam layer has a density less than about 7 mg collagen/cm².

17. An implant as in claim 1 wherein the foam layer comprises open cell foam.

18. An implant as in claim 1 wherein the fiber-reinforced film comprises partially hydrolyzed collagen.

19. An implant as in claim 1 wherein the fiber-reinforced film comprises oxidized collagen.

21. An implant as in claim 1 wherein the fiber-reinforced film comprises a macromolecular hydrophilic additive.

22. An implant as in claim 1 wherein the fiber-reinforced film comprises glycerine.

23. An implant as in claim 1 wherein the fiber-reinforced film comprises cross-linked collagen.

24. An implant as in claim 1 wherein the fiber-reinforced film comprises a bioabsorbable reinforcement member.

25. An implant as in claim 1 wherein the fiber-reinforced film comprises a multifilament reinforcement member.

26. An implant as in claim 1 wherein the fiber-reinforced film comprises an anti-adhesive agent.

2-7. -7. (canceled)