NON-INVASIVE MEASUREMENT OF BLOOD ANALYTES
First Claim
1. A method for measuring blood oxygen saturation in blood of a patient, comprising:
- placing against a body part of the patient an apparatus for non-invasive measurement of at least one analyte in the blood in the body part of the patient;
transmitting light via a plurality of transmitting fibers to the body part of the patient;
detecting light transmitted from, or reflected through, the body part of the patient via a plurality of light detector fibers;
determining a measurement of at least one analyte in the blood utilizing a non-pulsatile element of the blood; and
measuring blood oxygen saturation (SO2) using the equation;
SO2=100*(OXI+0.43)/1.5,wherein, OXI is the oxygenation index of the blood and is defined by the equation;
OXI=[(e−
d)/11.7−
(d−
c)/11.6]*100/HbI,wherein, HbI is the hemoglobin index of the blood and is defined by the equation;
HbI=[(b−
a)/27.1+(c−
b)/21.4+(c−
e)/23.3+(c−
f)/13.6]*100,and wherein;
a=absorption value at 500.9 nm wavelength of light;
b=absorption value at 528.1 nm wavelength of light;
c=absorption value at 549.5 nm wavelength of light;
d=absorption value at 561.1 nm wavelength of light;
e=absorption value at 572.7 nm wavelength of light; and
f=absorption value at 586.3 nm wavelength of light.
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Accused Products
Abstract
An apparatus for the measurement of at least one analyte in the blood of a patient, which includes a light source generating broadband light and a light-transmission arrangement having a plurality of transmitting fibers is positioned for simultaneously transmitting multiple wavelengths of the broadband light from the light source to the blood of the patient. The measurement apparatus further includes an optical fiber arrangement having a plurality of light detector fibers for leading multi-wavelength light, in spectrally unseparated form, transmitted through, or reflected from, the blood and a light detection arrangement for receiving the multi-wavelength light in its spectrally unseparated form from the optical fiber arrangement, for spectrally decomposing the received light, and for determining amplitudes of selected wavelengths of the decomposed light. The measurement apparatus utilizes a non-pulsatile element of the patient'"'"'s blood for determining the measurement of at least one analyte in the blood as a function of the amplitudes of the selected wavelengths.
80 Citations
1 Claim
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1. A method for measuring blood oxygen saturation in blood of a patient, comprising:
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placing against a body part of the patient an apparatus for non-invasive measurement of at least one analyte in the blood in the body part of the patient; transmitting light via a plurality of transmitting fibers to the body part of the patient; detecting light transmitted from, or reflected through, the body part of the patient via a plurality of light detector fibers; determining a measurement of at least one analyte in the blood utilizing a non-pulsatile element of the blood; and measuring blood oxygen saturation (SO2) using the equation;
SO2=100*(OXI+0.43)/1.5,wherein, OXI is the oxygenation index of the blood and is defined by the equation;
OXI=[(e−
d)/11.7−
(d−
c)/11.6]*100/HbI,wherein, HbI is the hemoglobin index of the blood and is defined by the equation;
HbI=[(b−
a)/27.1+(c−
b)/21.4+(c−
e)/23.3+(c−
f)/13.6]*100,and wherein; a=absorption value at 500.9 nm wavelength of light; b=absorption value at 528.1 nm wavelength of light; c=absorption value at 549.5 nm wavelength of light; d=absorption value at 561.1 nm wavelength of light; e=absorption value at 572.7 nm wavelength of light; and f=absorption value at 586.3 nm wavelength of light.
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Specification