Device and Method for Delivery of a Physiologically Active Substance Depending on a Measured Physiological Parameter
First Claim
1. A device for delivery of a physiologically active substance depending on a measured physiological parameter, the device comprising:
- a container for a perfusion fluid containing the physiologically active substance,a unit for delivery of the perfusion fluid containing the physiologically active substance into the body,a sensor for measuring the physiological parameter of the body by an analysis of the perfusion fluid after an at least partial equilibration of the perfusion fluid with a body fluid, anda unit, which is connected to the sensor, for controlling the quantity of the physiologically active substance to be delivered depending on the measured physiological parameter,wherein the sensor for measuring the physiological parameter is combined with the unit for delivery of the perfusion fluid containing the physiologically active substance, so that the measurement of the physiological parameter occurs essentially at the location of the delivery of the physiologically active substance.
1 Assignment
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Accused Products
Abstract
A device (10) for delivery of glucose-regulating medication depending on the measured tissue glucose concentration, having a sensor (7) for measuring the glucose concentration in the tissue fluid, possibly a unit (1) for removing fluid from subcutaneous tissue (11), as well as a container (14) for the medications, having a unit (23) for subcutaneous delivery of the glucose-regulating medications, and having a unit (12) connected to the glucose sensor (7) for regulating the delivery of the glucose-regulating medication depending on the measured tissue glucose concentrations. To provide a device (10) simulating the function of the natural pancreas and being compact, the sensor (7) for measuring the tissue glucose concentration or the unit (1) for removing the tissue fluid is combined with the delivery unit (23), particularly in a shared catheter (25), so that the measurement of the tissue glucose concentration is essentially performed at the location of the delivery of the glucose-regulating medication.
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Citations
58 Claims
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1. A device for delivery of a physiologically active substance depending on a measured physiological parameter, the device comprising:
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a container for a perfusion fluid containing the physiologically active substance, a unit for delivery of the perfusion fluid containing the physiologically active substance into the body, a sensor for measuring the physiological parameter of the body by an analysis of the perfusion fluid after an at least partial equilibration of the perfusion fluid with a body fluid, and a unit, which is connected to the sensor, for controlling the quantity of the physiologically active substance to be delivered depending on the measured physiological parameter, wherein the sensor for measuring the physiological parameter is combined with the unit for delivery of the perfusion fluid containing the physiologically active substance, so that the measurement of the physiological parameter occurs essentially at the location of the delivery of the physiologically active substance. - View Dependent Claims (2, 3, 4, 10, 11, 12, 13, 19, 20, 21, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 55, 56, 57, 58)
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5-9. -9. (canceled)
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15-17. -17. (canceled)
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22. (canceled)
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35-38. -38. (canceled)
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39. A method for the delivery of a physiologically active substance depending on a measured physiological parameter, the method comprising:
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delivering a perfusion fluid containing the physiologically active substance into a body, measuring the physiological parameter of the body by an analysis of the perfusion fluid after an at least partial equilibration of the perfusion fluid with a body fluid, and controlling the quantity of the physiologically active substance delivered depending on the measured physiological parameter, wherein the physiological parameter is measured essentially at the location at which the physiologically active substance is delivered. - View Dependent Claims (40, 41)
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42-54. -54. (canceled)
Specification