MICROPLATE AND METHODS OF USING THE SAME
First Claim
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1. A microplate comprising:
- a body defining a plurality of wells, each of the wells having at least one bottom portion configured to allow for transmission of X-rays during X-ray powder diffraction analysis with minimized background interference in the X-ray powder diffraction data.
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Abstract
Microplates having a body defining a plurality of wells, wherein the wells have at least one bottom portion configured to allow the sample to be analyzed by various methods in situ with minimized background interference in the data obtained, and methods of using the same, are disclosed. The improved microplate may also have wells having certain shapes and/or sizes to allow the sample to be analyzed with minimized background interference in the data obtained. A system for obtaining high-quality XRPD or Raman data is also disclosed.
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Citations
38 Claims
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1. A microplate comprising:
a body defining a plurality of wells, each of the wells having at least one bottom portion configured to allow for transmission of X-rays during X-ray powder diffraction analysis with minimized background interference in the X-ray powder diffraction data. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A microplate comprising:
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a body defining a plurality of wells, each of the wells having at least one bottom portion, wherein the at least one bottom portion comprises polypropylene and has a thickness ranging from about 1 micron to about 1 millimeter. - View Dependent Claims (9, 10)
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11. A method of reducing background interference in X-ray powder diffraction data, the method comprising:
obtaining the X-ray powder diffraction data on a sample in a microplate comprising a body defining a plurality of wells, wherein the wells have at least one bottom portion, and wherein the at least one bottom portion is configured to allow for transmission of X-rays with minimized background interference in the X-ray powder diffraction data. - View Dependent Claims (12, 13, 14, 15)
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16. A method of reducing background intereference in X-ray powder diffraction data, the method comprising:
obtaining the X-ray powder diffraction data on a sample in a microplate wherein the microplate comprises a body defining a plurality of wells, wherein the wells have at east one bottom portion, and wherein the at least one bottom portion comprises polypropylene and has a thickness ranging from about 1 micron to about 1 millimeter. - View Dependent Claims (17, 18)
- 19. A method of obtaining improved X-ray powder diffraction data on a sample comprising obtaining the X-ray powder diffraction data on a sample in a microplate wherein the microplate comprises a body defining a plurality of wells, wherein the wells have at least one bottom portion, and wherein the at least one bottom portion is configured to allow for transmission of X-rays with minimized background interference in the X-ray powder diffraction data.
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24. A system for obtaining improved X-ray powder diffraction data on a sample comprising an X-ray diffractometer and a microplate comprising a body defining a plurality of wells,
wherein the wells have at least one bottom portion, wherein the at least one bottom portion is configured to allow for transmission of X-rays with minimized background interference in the X-ray powder diffraction data, wherein the X-ray diffractometer comprises a plate holder, and wherein the microplate is loaded onto the plate holder and X-rays are transmitted through the sample and the bottom portion with minimized background interference from the at least one bottom portion.
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25. A method of reducing background interference in Raman data, the method comprising:
obtaining the Raman data on a sample in a microplate comprising a body defining a plurality of wells, wherein the wells have at least one bottom portion, and wherein the at least one bottom portion is configured to allow for transmission of Raman laser light with minimized background interference in the Raman data. - View Dependent Claims (26, 27, 28, 29)
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30. A method of reducing background interference in Raman data, the method comprising:
obtaining the Raman data on a sample in a microplate wherein the microplate comprises a body defining a plurality of wells, wherein the wells have at least one bottom portion, and wherein the at least one bottom portion comprises polypropylene and has a thickness ranging from about 1 micron to about 1 millimeter. - View Dependent Claims (31, 32)
- 33. A method of obtaining improved Raman data on a sample comprising obtaining the Raman data on a sample in a microplate wherein the microplate comprises a body defining a plurality of wells, wherein the wells have at least one bottom portion, and wherein the at least one bottom portion is configured to allow for transmission of Raman laser light with minimized background interference in the Raman data.
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38. A system for obtaining improved Raman data on a sample comprising a Raman spectrometer and a microplate comprising a body defining a plurality of wells,
wherein the wells have at least one bottom portion, wherein the at least one bottom portion is configured to allow for transmission of Raman laser light with minimized background interference in the Raman data, wherein the Raman spectrometer comprises a plate holder, and wherein the microplate is loaded onto the plate holder and Raman laser light is transmitted through the sample and the bottom portion with minimized background interference from the at least one bottom portion.
Specification