Cosmetic or Dermopharmaceutical Composition Comprising an Euglena Extract

• US 20090017147A1
• Filed: 01/13/2006
• Published: 01/15/2009
• Est. Priority Date: 01/14/2005
• Status: Active Grant

• Current Assignee: Sederma, Co.
• Original Assignee: Sederma, Co.
• Inventors: Lamy, Louis Francois, Mondon, Philippe, Lintner, Karl, Mas Chamberlin, Claire
• Granted Patent: US 8,741,357 B2
• Time in Patent Office: Days
• US Class Current: 424/780
• CPC Class Codes: A61K 8/9711 Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
• CPC Class Codes: A61K 8/9728 Fungi, e.g. yeasts
• CPC Class Codes: A61K 8/9767 Pinaceae [Pine family], e.g. pine or cedar
• CPC Class Codes: A61K 8/9771 Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
• CPC Class Codes: A61K 8/9789 Magnoliopsida [dicotyledons]
• CPC Class Codes: A61K 8/9794 Liliopsida [monocotyledons]
• CPC Class Codes: A61P 17/02 for treating wounds, ulcers, burns, scars, keloids, or the like
• CPC Class Codes: A61P 17/16 Emollients or protectives, e.g. against radiation
• CPC Class Codes: A61Q 17/00 Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/001 Preparations for care of the lips
• CPC Class Codes: A61Q 19/007 Preparations for dry skin
• CPC Class Codes: A61Q 19/06 for countering cellulitis
• CPC Class Codes: A61Q 19/08 Anti-ageing preparations
• CPC Class Codes: A61Q 5/00 Preparations for care of the hair

Abstract

The invention provides a cosmetic or dermopharmaceutic composition containing an Euglena extract, its use to activate the cellular metabolism and in particular to protect and/or improve the state of the skin and to reduce the signs of ageing in particular and/or cutaneous fatigue

Claims

1-19. -19. (canceled)

20. A cosmetic or dermopharmaceutical composition suitable for topical application to the skin containing an amount of an Euglena extract sufficient to reconstitute intracellular ATP in the skin cells, generate IP₃ in the skin cells, or trigger release of intracellular calcium in the skin cells to which it is applied, and a dermatologically acceptable carrier.

21. The cosmetic or dermopharmaceutical composition of claim 20, wherein the amount of an Euglena extract is sufficient to reconstitute intracellular ATP in the skin cells, generate IP₃ in the skin cells, and trigger release of intracellular calcium in the skin cells to which it is.

22. The cosmetic or dermopharmaceutical composition of claim 20, wherein the Euglena extract is includes a total phospholipid content of between about 0.002 and about 5%.

23. The cosmetic or dermopharmaceutical composition according to any one of claims 20, 21 and 22, wherein said Euglena extract is an Euglena gracilis extract.

24. The cosmetic or dermopharmaceutical composition according to any one of claims 20, 21 and 22, wherein said Euglena extract is present at a concentration from 0.01% (w/w) to 100% (w/w) by weight of the composition.

25. The cosmetic or dermopharmaceutical composition according to any one of claims 20, 21 and 22, further comprising at least one skin care active.

26. The cosmetic or dermopharmaceutical composition according to any one of claims 20, 21 and 22, further comprising a skin anti-aging agent, anti-wrinkle agent, anti-atrophy agent, anti-oxidant/radical scavenger or an energizing compound.

27. The cosmetic or dermopharmaceutical composition of claim 25, wherein said at least one skin care active is selected from the group consisting of peptidic compounds, vitamin A (retinol), vitamin E (tocopherol), alpha hydroxy acids (AHA), isoflavones, and active oxygen-generation inhibitors.

28. The cosmetic or dermopharmaceutical composition according to any one of claims 20, 21 and 22, wherein said Euglena extract is used in the form of a solution, dispersion, emulsion, paste, powder, macrocapsule, microcapsule, nanocapsule, macrosphere, microsphere, nanosphere, liposome, oleosome, chylomicron, macroparticle, microparticle, nanoparticle, macrosponge, microsponge, nanosponge or adsorbed on organic polymer powders, talcs, bentonites or other inorganic supports.

29. The cosmetic or dermopharmaceutical composition according to any one of claims 20, 21 and 22, wherein said composition is in the form of creams, lotions, ointments, milks, gels, emulsions, dispersions, solutions, suspensions, cleansers, foundations, anhydrous preparations (sticks, in particular lipsticks, body and bath oils), shower and bath gels, shampoos and scalp treatment lotions, cream or lotion for care of the skin or hair, sun-screen lotions, milks or creams, artificial suntan lotions, creams or creams, shaving creams or foams, aftershave lotions, mascaras or nail varnishes, lipsticks, skin “

essences,”

serums, adhesive or absorbent materials, transdermal patches, powders, emollient lotion, emollient milk, emollient cream, sprays, oils for the body and the bath, make up, foundation tint bases, pomade, colloid, compact or solid suspension, pencil, sprayable formulation, brossable.

30. The cosmetic or dermopharmaceutical composition of claim 24, wherein said Euglena extract is present at concentration from 0.1% (w/w) to 30% (w/w) by weight of the composition.

31. The cosmetic or dermopharmaceutical composition of claim 30, wherein said Euglena extract is present at concentration from 0.5% (w/w) to 5% (w/w) by weight of the composition.

32. A method for treating tired skin, for stimulating cellular metabolism, for affecting cutaneous chronobiology, for treating signs of aging, supplying the energy supplement necessary for regeneration of the skin, minimizing the cell dysfunctions induced by jetlag and/or by night work, for intervening at pigmentation level, for inhibiting melanogenesis, for stimulating the detoxification systems, for stimulating the growth of hair and body hair, for acting on adipocytes, for promoting lipolysis comprising topically applying the composition according to any one of claims 20, 21 and 22, to the skin of a subject in need thereof.

33. The method of claim 32, wherein said composition is applied to the skin at night for affecting cutaneous chronobiology.

34. A method of protecting, improving the state of the skin, and/or preventing and/or treating imperfections of the skin and/or hair and/or mucosa, and/or reducing the signs of cutaneous aging and/or fatigue comprising the steps of providing an amount of the composition according to any one of claims 20, 21 and 22, and applying same to the skin of a person in need thereof.

35. A method of treating and/or reducing skin dryness, loss of skin elasticity, withered and flaccid skin, sagging, dehydrated skin, loss of skin firmness, skin thinning, loss of skin tightness, loss of skin recoil from deformation, discoloration blotching, sallowness, hyperpigmented skin regions such as age spots and freckles, keratoses, abnormal differentiation, hyperkeratinization, elastosis, collagen breakdown and other histological changes in the stratum corneum, dermis, epidermis, the skin vascular system and underlying tissues, especially those proximate to the skin, dull, impaired hair, hair loss and dysequilibrium of the scalp comprising the steps of providing an amount of the composition according to any one of claims 20, 21 and 22, and applying same to the skin of a person in need thereof and applying same to the skin of a person in need thereof.