IMPLANTABLE MEDICAL DEVICE

• US 20090024054A1
• Filed: 07/10/2008
• Published: 01/22/2009
• Est. Priority Date: 07/20/2007
• Status: Abandoned Application

• Current Assignee: Biotronik VI Patent AG (Biotronik SE & Company KG)
• Original Assignee: Biotronik VI Patent AG (Biotronik SE & Company KG)
• Inventors: Albus, Marco, Kespohl, Stefanie, Lazarus, Arnaud, Bode, Sven, Elsner, Joachim
• Application Number:
  US12/170,868
• Publication Number:
  US 20090024054A1
• Time in Patent Office: Days
• US Class Current: 600/549
• CPC Class Codes: A61B 5/0008 Temperature signals
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/0537 Measuring body composition by impedance, e.g. tissue hydration or fat content
• CPC Class Codes: A61B 5/6846 specially adapted to be brought in contact with an internal body part, i.e. invasive

Abstract

The invention relates to an implantable medical device which has sensors for recognizing the health status of the bodily tissue surrounding the implantable medical device in a sensor.

Claims

1. An implantable medical device (10) comprising:

a housing (42), which contains a control unit (54);

a telemetry unit (58) connected to the control unit (54) for wireless signal transmission to an external device; and

,

at least one sensor (60;

70;

78;

79;

82) connected to the control unit (54), which is implemented to detect a tissue property characteristic for a tissue status of bodily tissue that surrounds the housing (42) after implantation of the implantable medical device (10).

2. The implantable medical device according to claim 1, wherein

the control unit (54) is implemented to process and analyze sensor output signals originating from the at least one sensor in such a manner that the control unit automatically assigns a particular sensor output signal or a plurality of chronologically coherent sensor output signals to a healthy tissue status or a pathological tissue status or an inflamed tissue status, and/or

the control unit (54) is implemented to assign the one or more of the sensor output signals to an inflamed tissue status, to detect the inflamed tissue status and then to transmit a warning signal via the telemetry unit (58) and/or to cause a suitable patient alarm if needed, and/or

the control unit (54) is implemented to analyze multiple sensor output signals in combination with one another to detect the pathological tissue status, and/or

the control unit (54) is implemented to cause a regular transmission of the sensor output signals via the telemetry unit (58) and/or to trigger the suitable patient alarm.

3. The implantable medical device according to claim 2, wherein

the control unit (54) is implemented to perform an assignment of one or more of the sensor output signals to a healthy tissue status or the pathological tissue status by comparison of one or more of the sensor output signals to characteristic comparison values.

4. The implantable medical device according to claim 1, wherein

the at least one sensor is a temperature sensor (79), which is implemented to detect a temperature of the bodily tissue surrounding the housing (42) after implantation of the implantable medical device (10) and

the control unit (54) is implemented to compare a temperature signal that originates from the temperature sensor (79) as a sensor output signal to a comparison temperature value and to detect the pathological tissue status if the comparison temperature value is exceeded.

5. The implantable medical device according to claim 4, wherein

the control unit (54) is implemented to detect the pathological tissue status and to then transmit a warning signal via the telemetry unit (58) and/or to cause a suitable patient alarm if needed if the temperature signal exceeds a temperature comparison signal, which corresponds to a predetermined temperature, which is between 37.0°

C. and 40°

C., for more than 12 hours.

6. The implantable medical device according to claim 1, wherein

the at least one sensor is a tissue fluid sensor (70;

82) and

the control unit (54) is implemented to detect a pathological tissue status and then to transmit a warning signal via the telemetry unit (58) and/or to cause a suitable patient alarm if needed if a sensor output signal of the tissue fluid sensor indicates a characteristic rise of a tissue fluid.

7. The implantable medical device according to claim 6, wherein

the control unit (54) is implemented to calculate a differential quotient of the sensor output signal of the tissue fluid sensor that represents a signal rise or drop and to detect the characteristic rise of the tissue fluid by comparison of the differential quotient to a predefined comparison value, and/or

the tissue fluid sensor is an impedance sensor (70) which has two electrodes (42, 81) situated on the housing of the implantable medical device for current feed and voltage measurement and which is implemented to measure an impedance that exists between the two electrodes and to generate a corresponding sensor output signal, and/or

the tissue fluid sensor has an ultrasonic transducer (82).

8. The implantable medical device according to claim 7, wherein

the control unit (54) is implemented to detect the characteristic rise of the tissue fluid based on a characteristic signal drop of the corresponding sensor output signal of the impedance sensor (70).

9. The implantable medical device according to claim 1, wherein

the at least one sensor is a pH value sensor (78), which is implemented to provide a sensor output signal that represents a pH value of bodily fluid that adjoins the housing after implantation of the implantable medical device, and

the control unit is implemented to respond to a drop of the pH value of the bodily fluid that surrounds the housing of the implantable medical device and to detect a pathological tissue status and then to transmit a warning signal via the telemetry unit (58) and/or to cause a suitable patient alarm if needed.

10. The implantable medical device according to claim 1, wherein

the implantable medical device (10) has an attitude sensor (60), which is implemented to detect an orientation of the implantable medical device (10) in relation to gravity'"'"'s direction, and

the control unit (54) is implemented to detect and analyze attitude sensor output signals over a period of time that lasts multiple days and to respond to a long-term, permanent change of the attitude sensor output signals which indicates a change of relative position between the implantable medical device (10) and a patient body in which the implantable medical device (10) is implanted and then to transmit a warning signal via the telemetry unit (58) and/or to cause a suitable patient alarm if needed, and/or

the control unit (54) is implemented to prepare a particular daily histogram of the attitude sensor output signals and to detect a permanent shift in a form of sequential daily histograms.

11. The implantable medical device according to claim 1, wherein

the telemetry unit (58) has a high-frequency transmitter and receiver and is implemented in combination with the control unit (54) to detect an electrical permittivity of surroundings of the implantable medical device (10), and/or

the control unit (54) is implemented to detect the electrical permittivity at regular time intervals and to detect a change of the electrical permittivity as a sign of a change of the tissue status and to transmit a warning signal via the telemetry unit (58) and/or to cause a suitable patient alarm if needed, and/or

the control unit (54) is implemented to detect the electrical permittivity once to five times daily.

12. The implantable medical device according to claim 2, wherein

the control unit (54) is implemented to detect a simultaneous rise of a temperature signal and a sensor output signal of a tissue fluid sensor that indicates a characteristic rise of a tissue fluid and then to transmit a warning signal via the telemetry unit (58) and/or to cause a suitable patient alarm if needed.

13. The implantable medical device according to claim 2, wherein

the control unit (54) is implemented to detect a simultaneous rise of a temperature signal, a sensor output signal of a tissue fluid sensor (70;

82) that indicates a characteristic rise of a tissue fluid, and a sensor output signal of a pH value sensor (78) that characterizes a drop of the pH value and then to transmit a warning signal via the telemetry unit (58) and/or to cause a suitable patient alarm if needed.

14. The implantable medical device according to claim 2, wherein

the implantable medical device (10) has a controllable medication depot (83), which is connected to the control unit (54) and is implemented to discharge a medication to surroundings of the implantable medical device (10) upon a control signal of the control unit (54), and

the control unit (54) is implemented to output a control signal to the medication depot upon detection of the pathological tissue status, which causes a medication discharge by the medication depot (83), and/or

the medication depot (83) contains an anti-inflammatory medication.

15. The implantable medical device according to claim 14, wherein

the implantable medical device contains medication selected from the group of steroids, dexamethasone and/or prednisone.