SYSTEM AND METHOD FOR INTRACRANIAL ACCESS

• US 20090030400A1
• Filed: 07/23/2008
• Published: 01/29/2009
• Est. Priority Date: 07/25/2007
• Status: Abandoned Application

• Current Assignee: Penumbra, Inc.
• Original Assignee: Penumbra, Inc.
• Inventors: Barry, David, Hui, Delilah, Bose, Arani, Tompkins, Ben
• Application Number:
  US12/178,521
• Publication Number:
  US 20090030400A1
• Time in Patent Office: Days
• US Class Current: 604/510
• CPC Class Codes: A61M 2025/0046 Coatings for improving slidability
• CPC Class Codes: A61M 25/0023 by the form of the lumen, e.g. cross-section, variable diameter
• CPC Class Codes: A61M 25/005 with embedded materials for reinforcement, e.g. wires, coils, braids
• CPC Class Codes: A61M 25/0053 having a variable stiffness along the longitudinal axis, e.g. by varying the pitch of the coil or braid
• CPC Class Codes: A61M 25/0054 with regions for increasing flexibility
• CPC Class Codes: A61M 25/0068 Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
• CPC Class Codes: A61M 25/008 Strength or flexibility characteristics of the catheter tip
• CPC Class Codes: A61M 25/0108 using radio-opaque or ultrasound markers
• CPC Class Codes: A61M 27/006 Cerebrospinal drainage; Accessories therefor, e.g. valves

Abstract

A delivery catheter for accessing the intra-cranial vascular includes a rigid proximal section and a distal section having an outer diameter and flexibility suitable for advancement into the intra-cranial vasculature, such as the Petrous segment or the Cavernous segment of the internal carotid artery. The wall thickness and rigidity of the catheter decrease from the proximal section to the distal section, preferably in discrete segments each having reduced wall thickness and/or durometer relative to proximally adjacent sections. An intra-cranial access system includes the delivery catheter and a selection catheter insertable through the lumen of the delivery catheter. The selection catheter is shaped to facilitate selection of the target branch of the neurovasculature off the aortic arch and allows the delivery catheter to be advanced over the selection catheter into the selected branch.

Claims

1. A method of accessing the intracranial vasculature, comprising the steps of:

inserting a delivery catheter percutaneously into the arterial system, and advancing a distal end of the delivery catheter to the cranial vasculature distal to the cervical segment of the internal carotid artery.

2. The method of claim 1, wherein the method includes advancing the distal end into the internal carotid artery.

3. The method of claim 2, wherein the method includes advancing the distal end at least to the Petrous segment of the internal carotid artery.

4. The method of claim 2, wherein the method includes advancing the distal end at least to the Cavernous segment of the internal carotid artery.

5. The method of claim 1, wherein advancing the distal end distal to the cervical segment of the carotid artery includes:

advancing the distal end of the delivery catheter to the aortic arch;

passing a selection catheter through the delivery catheter, the selection catheter having a shaped distal portion;

with the distal end of the delivery catheter in the aortic arch, advancing the shaped distal portion of the selection catheter from the distal end of the delivery catheter, causing the shaped distal portion to advance into a selected arterial branch distal to the aortic arch; and

advancing the delivery catheter over the selection catheter into the selected arterial branch.

7. The intracranial access system according to claim 6, further including instructions for use instructing the user to use the system to gain access to intracranial vasculature according to the method of claim 1, 2, 3, 4 or 5.

6. An intracranial access system, comprising:

a delivery catheter having a delivery catheter lumen, a proximal end and a distal end, the delivery catheter including a plurality of sections, each section having greater flexibility than the section proximally adjacent to it; and

a selection catheter having selection catheter lumen and a pre-shaped distal portion, the selection catheter insertable through the delivery catheter lumen; and

at least one guidewire insertable through the selection catheter lumen.

8. An intracranial delivery catheter comprising:

an elongate tubular member having a delivery catheter lumen, a proximal end and a distal end, the delivery catheter including a plurality of discrete sections each having a wall thickness and a tubular polymeric portion having a durometer, wherein at least one of the wall thickness and durometer of each section is lower than that of the proximally adjacent section.

9. The delivery catheter of claim 8, wherein the elongate tubular member includes a distal end having a maximum outer diameter of approximately 0.07 in.

10. The delivery catheter of claim 8, wherein the most proximal one of the plurality of sections has a length of at least approximately 81 cm.

11. The delivery catheter of claim 8, wherein the most proximal one of the plurality of sections has a tubular polymeric portion having a durometer of at least approximately 80D.

12. The delivery catheter of claim 11, wherein a distal one of the plurality of sections has a tubular polymeric portion having a durometer of 35D or lower.

13. The delivery catheter of claim 11, wherein a distal one of the plurality of sections has a tubular polymeric portion having a durometer of 80A or lower.

14. The delivery catheter of claim 8, wherein the plurality of sections includes at least two proximal sections each having a tubular polymeric portion having a durometer of 80D or higher, each of the two proximal sections having a different wall thickness.

15. The delivery catheter of claim 14, wherein the plurality of sections further includes a distal section having a tubular polymeric portion having a durometer of 80A or lower.

16. The delivery catheter of claim 15, wherein the plurality of sections further includes at least four intermediate sections between the proximal sections and the distal sections, the intermediate sections having tubular polymeric portions having durometers in the range of 72D-40D.

17. An intracranial delivery catheter comprising:

an elongate tubular member having a delivery catheter lumen and a distal end, the delivery catheter proportioned to extend intravascularly from a femoral access point in a human patient to an intra-cranial blood vessel, the elongate tubular member including;

a proximal portion including at least two rigid proximal segments, the proximal portion proportioned to extend from a femoral access point through an aortic arch;

an intermediate portion including at least two intermediate segments, the intermediate section proportioned to extend intravascularly from an aortic arch through a cervical region of the vasculature, at least one of the intermediate segments having an outer diameter smaller than the outer diameter of the at least two rigid proximal segments; and

a distal portion including at least two distal segments proportioned to extend intravascularly from a base of a skull to an intra-cranial blood vessel, at least one of the distal segments having an outer diameter smaller than the outer diameter of the at least two intermediate segments.

18. The delivery catheter of claim 17, wherein at least one of the distal segments has a maximum outer diameter of approximately 0.07 inches.

19. The delivery catheter of claim 17, wherein at least one of the proximal segments is formed of a material having a stiffness of at least approximately 80D, and wherein at least one of the distal segments is formed of a material having a stiffness of approximately 80A or less.